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Treatment of persistent epithelial defects in neurotrophic keratitis with epidermal growth factor: a preliminary open study

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Abstract

We report three patients with persistent epithelial defects in the context of neurotrophic keratopathy that healed while on treatment with topically applied, mouse-derived epidermal growth factor (m-EGF). The clinical course of these patients was striking and suggests that EGF may have a potential role in the treatment of persistent epithelial defects in subjects suffering from neurotrophic keratitis.

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Correspondence to: S. Daniele

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Daniele, S., Gilbard, J.P. & Schepens, C.L. Treatment of persistent epithelial defects in neurotrophic keratitis with epidermal growth factor: a preliminary open study. Graefe's Arch Clin Exp Ophthalmol 230, 314–317 (1992). https://doi.org/10.1007/BF00165937

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  • DOI: https://doi.org/10.1007/BF00165937

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