Abstract
• Background: Nevus of Ota is common in Japanese women, but most patients are not examined ophthalmologically. • Methods: We performed ophthalmologic examinations on 16 Japanese women who had had bluish pigmentation in the periorbital region, sclera, and conjunctiva since birth. • Results: Fifteen patients had unilateral involvement, and one had bilateral lesions. The visual acuities were good, and the intraocular pressures were within normal range. All patients had a negative family history. Three patients had light pigmentation in the optic disc in the affected eye. • Conclusion: We believe that optic disc pigmentation associated with nevus of Ota, as found in these three patients, may be common but have been rarely described.
Similar content being viewed by others
References
Albert DM, Scheie HG (1963) Nevus of Ota with malignant melanoma of the choroid. Arch Ophthalmol 69:774–777
Cowan TH, Balistocky M (1961) The nevus of Ota or oculodermal melanocytosis. The ocular change. Arch Ophthalmol 65:483–492
Enriquez R, Egbert B, Bullock J (1973) Primary malignant melanoma of central nervous system. Pineal involvement in a patient with nevus of Oto and multiple pigmented skin nevi. Arch Pathol 95: 392–395
Fishman GRA, Anderson R (1962) Nevus of Ota. Report of two cases, one with open-angle glaucoma. Am J Ophthalmol 54:453–457
Fitzpatrick TB, Zellar R, Kukita A, Kitamura H (1956) Ocular and dermal melanocytosis. Arch Ophthalmol 56:830–832
Font RL, Reynolds AM Jr, Zimmerman LE (1967) Diffuse malignant melanoma of the iris in the nevus of Ota. Arch Ophthalmol 77:513–518
Frezzotti, Guerra R, Dragoni GP, Bonanni P (1968) Malignant melanoma of the choroid in a case of naevus of Ota. Br J Ophthalmol 52:922–924
Gonder JR, Schields JA, Albert DM (1981) Malignant melanoma of the choroid associated with oculodermal melanocytosis. Ophthalmology 88:372–376
Gupta GP, Gangwar DN (1965) Naevus of Ota. Br J Ophthalmol 49:364–368
Hagler WS, Brown CC (1966) Malignant melanoma of the orbit arising in a nevus of Ota. Trans Am Acad Ophthalmol Otolaryngol 70:817–822
Halasa A (1970) Malignant melanoma in a case of bilateral nevus of Ota. Arch Ophthalmol 84:176–178
Hidano A, Kajima H, Ikeda S, Mizutani, Miyasato H, Niimura M (1967) Natural history of nevus of Ota. Arch Dermatol 95:187–195
Jay B (1965) Malignant melanoma of the orbit in a case of oculodermal melanosis (naevus of Ota). Br J Ophthalmol 49:359–363
Jensen CDF, Haffly GN (1948) An unusual case of progressive melanosis oculi. Am J Ophthalmol 31:1476–1479
Mishima Y, Mevorah B (1961) Nevus Ota and nevus Ito in American negroes. J Invest Dermatol 36:133–154
Ota M, Tanino H (1939) Naevus fuscocaeruleus ophthalmomaxillaris. Tokyo Med J 63:1243–1245
Roy PE, Schaeffer EM (1967) Nevus of Ota and choroidal melanoma. Surv Ophthalmol 12:130–140
Sang DN, Albert DM, Sober AJ, McMeekin TO (1979) Nevus of Ota with contralateral cerebral melanoma. Arch Ophthalmol 95:1820–1824
Spencer WH (1986) Optic nerve. In: Spencer WH (ed) Ophthalmic pathology, vol 3. Saunders, Philadelphia, pp 2337–2458
Suzuki T (1991) Studies of Ota's nevus. Statistical and photomicroscopic observations. J Jpn Plast Reconstr Surg 11:532–551
Velazquez N, Jones IS (1983) Ocular and oculodermal melanocytosis associated with uveal melanoma. Ophthalmology 90:1472–1476
Yamamoto T (1969) Malignant melanoma of the choroid in the nevus of Ota. Ophthalmologica 159:1–10
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kono, T., Kurome, H., Shibuya, Y. et al. Ocular findings in Japanese women with nevus of Ota. Graefe's Arch Clin Exp Ophthalmol 233, 667–671 (1995). https://doi.org/10.1007/BF00164667
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00164667