Skip to main content
Log in

Clinical application of motion-onset visual evoked potentials

  • Published:
Documenta Ophthalmologica Aims and scope Submit manuscript

Abstract

The results of motion-onset visual evoked potentials and pattern-reversal visual evoked potentials were compared in 5 adults with amblyopia, in 13 patients with unilateral retrobulbar neuritis and in 62 patients with multiple sclerosis. While the pattern-reversal visual evoked potentials had reduced amplitudes and prolonged latencies in all amblyopic eyes, the motion-onset visual evoked potentials were normal. Thus, motion-onset visual evoked potentials cannot be used for diagnosis of amblyopia. In patients with retrobulbar neuritis, both types of visual evoked potentials were delayed on stimulation of the affected eye. The latency increase was, however, greater for pattern-reversal visual evoked potentials than for motion-onset visual evoked potentials. Examination of the patients with multiple sclerosis showed that the additional use of motion-onset visual evoked potentials increased the sensitivity of the investigation. In some patients, only the motion-onset visual evoked potentials had pathologic latency increases, whereas the pattern-reversal visual evoked potentials stayed within normal limits.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Spehlmann R. Evoked potential primer: Visual, auditory, and somatosensory evoked potentials in clinical diagnosis. Stoneham, Mass: Butterworth Publishers, 1985: 85–7.

    Google Scholar 

  2. Kuba M, Kubová Z. Visual evoked potentials specific for motion-onset. Doc Ophthalmol 1992; 80: 83–89.

    Google Scholar 

  3. Kubová Z, Kuba M, Vít F, Peregrin J. Properties of movement on related VERs. Doc Ophthalmol 1990; 75: 67–72.

    Google Scholar 

  4. Markwardt F, Göpfert E, Müller R. Influence of velocity, temporal frequency and initial phase position of grating patterns on motion VEP. Biomed Biochim Acta 1988; 47: 753–60.

    Google Scholar 

  5. Arden GB, Barnard WM. Effect of occlusion on the visual evoked response in amblyopia. Trans Ophthalmol Soc UK 1979; 99: 419–26.

    Google Scholar 

  6. Mayeles WP, Moulholand WV. The response to pattern reversal in amblyopia. In: Gracco RQ, Bodis Wollner I, eds. Evoked potentials. New York: Alan R. Liss Inc, 1986: 243–50.

    Google Scholar 

  7. Levi DM, Manny Ruth E. The VEPs in the diagnostic evaluation of amblyopia. In: Gracco RQ, Bodis Wollner I, eds. Evoked postentials. New York: Alan R. Liss Inc, 1986: 437–46.

    Google Scholar 

  8. Sokol S. Clinical application of the ERG and VEPs in the pediatric age group. In: Gracco RQ, Bodis Wollner I, eds. Evoked potentials. New York: Alan R. Liss Inc, 1986: 447–55.

    Google Scholar 

  9. Halliday AM, McDonald WI, Mushin J. Delayed visual evoked responses in optic neuritis. Lancet 1972; i: 982–5.

    Google Scholar 

  10. Cox TA, Thompson HS, Hayereh SS, Snyder JE. Visual evoked potential and pupillary signs. A comparison in optic nerve disease. Arch Ophthalmol 1982; 100: 1603–7.

    Google Scholar 

  11. Sanders EACM, Volkers ACW, Van der Poel JC, Van Lith GHM. Visual function and pattern visual evoked response in optic neuritis. Br Ophthalmol 1987; 71: 602–8.

    Google Scholar 

  12. Brecelj J, Kriss A Pattern reversal VEPs in optic neuritis. Advantages of central and peripheral half-field stimulation. Neuro-ophthalmology 1989; 9: 55–63.

    Google Scholar 

  13. Harding AM, McDonald WI, Mushin J. Visual evoked potentials in patients with demyelinating disease. In: Desmedt JE, ed. Visual evoked potentials in man. New develop- ments. Oxford, England: Clarendon Press, 1977: 438–49.

    Google Scholar 

  14. Koerner E, Ladurner G, Flooh E, Reinhart B, Wolf R, Lechner H. Änderungen der Muster-evozierten Potentiale bei multipler Sklerose im Zusammenhang mit dem zietlichen Ablauf der Erkrankung. Z EEG-EMG 1982; 13: 73–6.

    Google Scholar 

  15. Matthews WB, Wattam-Bell JRB, Pountney E. Evoked potentials in the diagnosis of multiple sclerosis: A follow up study. J. Neurol Neurosurg Psychiatry 1982; 45: 303–7.

    Google Scholar 

  16. Oepen G, Brauner C, Doerr M, Thoden W. Visual evoked potentials elicited by checkerboard versus foveal stimulation in multiple sclerosis. Arch Psychiatr Nervenkr 1981; 229: 305–13.

    Google Scholar 

  17. Celesia GG, Kauffmann D, Cone S. Simultaneous recording of pattern electroretinography and visual evoked potentials in multiple sclerosis: A method to separate demyelinization from axonal damage to optic nerve. Arch Neurol 1986; 43: 1247.

    Google Scholar 

  18. Paty DW, Oger JJF, Kastrukoff LF, Hashimoto SA, Hooge JP, Eisen AA, Eisen KA, Purves SJ, Low MD, Brandejs V, Robertson WD, Li DKB. MRI in the diagnosis of MS. A prospective study with comparison of clinical evaluation, evoked potentials, oligoclonal banding, and CT. Neurology 1988; 38: 180–5.

    Google Scholar 

  19. Altenmüller E, Diener HC, Dichghans J. Visuel evozierte potentiale. In: Stöhr M, Dichghans J, Buettner UW, eds. Evozierte potenciale. Berlin: Springer Verlag, 1989: 279–379.

    Google Scholar 

  20. Lennie P, Trevarthen C, Van Essen D, Wässle A. Parallel processing of visual information. In: Spillmann L, Werner JS, eds. Visual perception: The neurophysiological foundations. San Diego: Academic Press, 1990: 103–28.

    Google Scholar 

  21. Wald G, Burian HM. The dissociation of form vision and light perception in strabismic amblyopia. Am J Ophthalmol 1944; 27: 950–63.

    Google Scholar 

  22. Feinsod M, Abramsky O, Auerbach E. Electrophysiological examination of the visual system in multiple sclerosis. J Neurol Sci 1973; 20: 161–75.

    Google Scholar 

  23. Hennerici M, Wenzel D, Freund HJ. The comparison of small-size rectangle and checkerboard stimulation for the evaluation of delayed visual evoked responses in patients suspected of MS. Brain 1977; 100: 119–36.

    Google Scholar 

  24. Gerhard H, Jörg J, Friesacher H. Zerebrale Refraktörperiod des VEP nach Ganzfeld- und fovealer Stimulation. Z EEG-EMG 1985; 16: 81–6.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kubová, Z., Kuba, M. Clinical application of motion-onset visual evoked potentials. Doc Ophthalmol 81, 209–218 (1992). https://doi.org/10.1007/BF00156010

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00156010

Key words

Navigation