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Biomaterials in the reconstruction of the human middle ear

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The use of biomaterials for reconstruction of the ossicular chain in middle ear involves a different approach from that associated with other regions of the organism. The features of the implantation site and the composition of the prosthesis are responsible for functional failures that result from deterioration or extrusion of the implant. Since the fifties, different types of materials, both biological and synthetic, have been employed in the attempt to achieve the ideal middle ear prosthesis. We present a reprospective study of 166 patients who underwent ossicular chain reconstruction involving autografts and homografts of cartilage or auditory ossicle (n=104) or synthetic prostheses (n=62). We compare prostheses of different compositions on the basis of the cases of extrusion and the histological deterioration encountered with each. In our experience, polymers are associated with frequent extrusion and deterioration of the biomaterial, while the results are better with biological implants and those made of hydroxyapatite.

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Authors and Affiliations

  1. Servicio de Otorrinolaringología Clínica Puerta de Hierro, Universidad Autónoma de Madrid, Madrid, Spain

    M. Pinilla, J. R. García Berrocal & R. Ramírez-Camacho

  2. Departamento de Morfología Celular, Universidad de Alcalá de Henares, Madrid, Spain

    J. Bujan

  3. Servicio de Cirugía Experimental, Clinica Puerta de Hierro, Universidad Autónoma de Madrid, Madrid, Spain

    E. Jorge Herrero

Authors
  1. M. Pinilla
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  2. J. R. García Berrocal
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  3. R. Ramírez-Camacho
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  4. J. Bujan
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  5. E. Jorge Herrero
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Pinilla, M., García Berrocal, J.R., Ramírez-Camacho, R. et al. Biomaterials in the reconstruction of the human middle ear. J Mater Sci: Mater Med 6, 745–748 (1995). https://doi.org/10.1007/BF00134311

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  • DOI: https://doi.org/10.1007/BF00134311

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