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Production of L-DOPA from pyrocatechol and DL-serine by bioconversion using immobilized Erwinia herbicola cells

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Summary

Immobilized cells of Erwinia herbicola were used for L-DOPA production from pyrocatechol and DL-serine. Optimal conditions have been defined and utilized in batch and continuous reactors. A maximal volumetric productivity of 0.46 g/l.h in L-DOPA was obtained with a conversion yield of 18% (L-DOPA concentration 2.3 g/l).

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Authors and Affiliations

  1. Université de Provence, Laboratoire de Chimie Bactérienne, CNRS, BP 71, 13277, 9, Marseille, France

    G. Para, S. Rifai & J. Baratti

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  1. G. Para
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  2. S. Rifai
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  3. J. Baratti
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Para, G., Rifai, S. & Baratti, J. Production of L-DOPA from pyrocatechol and DL-serine by bioconversion using immobilized Erwinia herbicola cells. Biotechnol Lett 6, 703–708 (1984). https://doi.org/10.1007/BF00133060

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