Abstract
DNA synthesis was inhibited during embryogenesis of Habrotrocha rosa with mitomycin C and hydroxyurea. Inhibition of DNA replication in early stages of embryogenesis, at the beginning of organogenesis, just after cavitation of the stomodeum, resulted in a complete inhibition of further development. After this stage of embryogenesis development was insensitive to inhibition of DNA replication.
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References
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Plasota, K., Plasota, M. & Kunicki-Goldfinger, W.J.H. Macromolecular synthesis during embryogenesis of Habrotrocha rosa Donner I. Replication of DNA. Hydrobiologia 104, 147–148 (1983). https://doi.org/10.1007/BF00045961
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DOI: https://doi.org/10.1007/BF00045961