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Similarities and Differences in Neuroimaging

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Substance and Non-substance Addiction

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1010))

Abstract

Addiction is a chronically relapsing disease characterized by drug intoxication, craving, bingeing, and withdrawal with loss of control. An increasing number of studies have indicated that non-substance addiction, like internet addiction and pathological gambling, share clinical, phenomenological, and biological features with substance addiction. With the development of imaging technology in the past three decades, neuroimaging studies have provided information on the neurobiological effects, and revealed neurochemical and functional changes in the brains of both drug-addicted and non-substance addicted subjects. Imaging techniques play a more critical role in understanding the neuronal processes of addiction and will lead the direction in future research for medication development of addiction treatment, especially for non-substance addiction, which shares an increasing percentage of addiction disorder. This article will review the similarities and differences between substance and non-substance addiction based on neuroimaging studies that may provide clues for future study on these two main kinds of addiction, especially the growing non-substance addiction.

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Authors and Affiliations

  1. Department of Pharmacology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, 100191, China

    Yan-Kun Sun

  2. National Institute on Drug Dependence, Peking University, No. 38, Xueyuan Road, Haidian District, Beijing, 100191, China

    Yan-Kun Sun, Yan Sun & Jie Shi

  3. Peking-Tsinghua Center for Life Sciences and PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, China

    Xiao Lin

  4. Institute of Mental Health/Peking University Sixth Hospital and National Clinical Research Center for Mental Disorders & Key Laboratory of Mental Health, Peking University, Beijing, 100191, China

    Lin Lu

Authors
  1. Yan-Kun Sun
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  2. Yan Sun
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  3. Xiao Lin
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  4. Lin Lu
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  5. Jie Shi
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Correspondence to Jie Shi .

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Editors and Affiliations

  1. Key Laboratory of Brain Function and Disease, Chinese Academy of Sciences, and School of Life Sciences, University of Science & Technology of China, Hefei, Anhui, China

    Xiaochu Zhang

  2. National Institute on Drug Dependence, Peking University, Beijing, China

    Jie Shi

  3. Department of Psychological Medicine, PLA Army General Hospital, Beijing, China

    Ran Tao

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Sun, YK., Sun, Y., Lin, X., Lu, L., Shi, J. (2017). Similarities and Differences in Neuroimaging. In: Zhang, X., Shi, J., Tao, R. (eds) Substance and Non-substance Addiction. Advances in Experimental Medicine and Biology, vol 1010. Springer, Singapore. https://doi.org/10.1007/978-981-10-5562-1_5

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