Abstract
Mass spectrometry is a powerful approach for generating precise, accurate and sensitive quantitative information on the components of a complex sample. This chapter addresses the importance of quantification and the key considerations in the process of developing and performing a quantitative analysis. Rather than providing specific details, the focus here is on introducing the most important considerations associated with developing a quantitative analysis.
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Notes
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There is always a client or end-user of any data that the analytical scientist generates. It is essential for the analyst to be mindful of how the data they generate will be used.
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The author thanks Dr. Alex Nickel, Biodesix Inc., for helpful discussions during the preparation of this manuscript.
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Duncan, M.W. (2017). Primary Considerations in Quantitative Mass Spectrometry. In: Banoub, J., Caprioli, R. (eds) Molecular Technologies for Detection of Chemical and Biological Agents. NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht. https://doi.org/10.1007/978-94-024-1113-3_6
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DOI: https://doi.org/10.1007/978-94-024-1113-3_6
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