Non-Subjective Diagnosis of Arthritic Disorders by Multivariate Analysis of IR Spectra of Synovial Fluid

Abstract

Arthritis is the commonest disabling disease in the developed world, the 100 diseases classified as arthritis affecting over 4 million people in Canada alone. Despite the widespread occurrence and associated social and economic costs, arthritis remains difficult to diagnose and stage, in part due to the non-specific nature of many of the symptoms. Current diagnostic methods rely upon X-ray investigations and the experience of a rheumatologist. In addition, clinical laboratory tests are often required. Diagnosis by these methods involves subjectivity, is usually only possible when considerable damage to the joint has already occurred and is costly and time consuming. A non-subjective method for the rapid diagnosis of arthritis would be of great benefit.