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Biomaterials in Hand Surgery pp 107–125Cite as

Research Trends for Flexor Tendon Repair

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Abstract

Basic science research on the biology, repair, and rehabilitation of intrasynovial flexor tendon injuries has led to major advances in the clinical management of these injuries. Clinically applicable animal models have been developed to test novel treatments prior to clinical use. Initial research efforts focused on improving the biomechanics of the suture repair and reducing adhesions during healing through passive motion rehabilitation. Recent trends for flexor tendon repair include biological and biomaterial approaches to improve healing. Treatment of the tendon surface with natural and synthetic materials has led to dramatic improvements in the gliding properties of the tendons, and hence the function of the digit. Development of biofactor delivery systems has allowed investigators to test the effects of growth factors for enhanced flexor tendon healing. Application of these new biomaterials to intrasynovial flexor tendon repair has the potential to improve both tendon function (by improving the gliding properties of the tendon) and tendon strength (by enhancing extracellular matrix synthesis).

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Authors and Affiliations

  1. Orthopedic Surgery and Biomedical Engineering, Washington University, St. Louis, MO, USA

    S. Thomopoulos

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  1. S. Thomopoulos
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Editors and Affiliations

  1. Orthopaedics and Hand Surgery, The Catholic University School of Medicine, Rome, Italy

    Antonio Merolli

  2. School of Mechanical and Systems Engineering, Newcastle University, Newcastle upon Tyne, UK

    Thomas J. Joyce

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© 2009 Springer-Verlag Italia

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Thomopoulos, S. (2009). Research Trends for Flexor Tendon Repair. In: Merolli, A., Joyce, T.J. (eds) Biomaterials in Hand Surgery. Springer, Milano. https://doi.org/10.1007/978-88-470-1195-3_8

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  • DOI: https://doi.org/10.1007/978-88-470-1195-3_8

  • Publisher Name: Springer, Milano

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  • Online ISBN: 978-88-470-1195-3

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