Abstract
Neurofibrillary tangles, Pick bodies and Lewy bodies are considered quantitatively in relation to neuron loss. It would seem that the inclusions are not themselves the cause of neuron death.
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References
Gomez-Isla T, Hollister R, West H, Mui S, Growdon IH, Petersen RC, Parisi J, Hyman BT (1997) Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer’s disease. Ann Neurol 41: 17 – 24
Hansen LA, Daniel SE, Wilcock GK, Love S (1998) Frontal cortical synaptophysin in Lewy body diseases: relation to Alzheimer’s disease and dementia. J Neurosurg Psych 64: 653 – 656
Morsch R, Simon W, Coleman PD (1999) Neurons may live for decades with neurofibrillary tangles. J Neuropath Exp Neurol 58: 188 – 197
Suzuki K, Terry RD (1967) Fine structural localization of acid phosphatase in senile plaques in Alzheimer’s presenile dementia. Acta Neuropath 8: 276 – 284
Terry RD (1998) The cytoskeleton in Alzheimer’s disease. J Neural Transm [Suppl] 53: 141 – 145
Terry RD, Peck A, Deteresa R, Schechter R, Horoupian DS (1981) Some morphometric aspects of the brain in senile dementia of the Alzheimer’s type. Ann Neurol 10: 184 – 192
Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R (1991) Physical basis of cognitive alterations in Alzheimer’s disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 30: 572 – 580
Terry RD, Masliah E, Hansen LA (1994) Structural basis of the cognitive alterations in Alzheimer’s disease. In: Alzheimer’s disease, Raven Press, New York, p 187
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© 2000 Springer-Verlag
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Terry, R.D. (2000). Do neuronal inclusions kill the cell?. In: Jellinger, K., Schmidt, R., Windisch, M. (eds) Advances in Dementia Research. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6781-6_12
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DOI: https://doi.org/10.1007/978-3-7091-6781-6_12
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Print ISBN: 978-3-211-83512-8
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