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Experimental Models of Head Trauma

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Research and Publishing in Neurosurgery

Part of the book series: Acta Neurochirurgica Supplements ((NEUROCHIRURGICA,volume 83))

Summary

Traumatic brain injury is one of the most common causes for chronic disability in young people. Despite this there are currently no widely available modes of therapy that would limit the extent of brain damage secondary to trauma. Therefore, new insights into the pathological mechanisms involved in head trauma possibly leading to the identification of new therapeutic targets are urgently needed. In order to attain these goals adequate animal models for traumatic brain injury are needed. In the following paper the authors will review the various animal models for head trauma and emphasize their potential strengths and weaknesses.

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Author information

Authors and Affiliations

  1. Department of Neurology and the Agnes Ginges Center for Human Neurogenetics, Hebrew University-Hadassah Medical School, Hadassah University Hospital, Jerusalem, Israel

    R. R. Leker M.D.

  2. Department of Pharmacology, School of Pharmacy, Hebrew University-Hadassah Medical School, Jerusalem, Israel

    E. Shohami

  3. Department of Pediatric Neurosurgery, Tel-Aviv-Sourasky Medical Center and the Tel Aviv University, Tel Aviv, Israel

    S. Constantini

  4. Department of Neurology, Hadassah University Hospital, Ein Kerem, P.O. Box 12000, Jerusalem, 91120, Israel

    R. R. Leker M.D.

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  1. R. R. Leker M.D.
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  1. Ankara, Turkey

    Y. Kanpolat

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Leker, R.R., Shohami, E., Constantini, S. (2002). Experimental Models of Head Trauma. In: Kanpolat, Y. (eds) Research and Publishing in Neurosurgery. Acta Neurochirurgica Supplements, vol 83. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6743-4_9

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  • DOI: https://doi.org/10.1007/978-3-7091-6743-4_9

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-7399-2

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