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Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma

  • Conference paper
Local Therapies for Glioma Present Status and Future Developments

Part of the book series: Acta Neurochirurgica Supplements ((NEUROCHIRURGICA,volume 88))

Abstract

Our group have developed a new method of drug delivery into the brain using implantable biodegradable microspheres. In this mini-review, we describe the development, preclinical studies and clinical trials involving 5-fluorouracil-releasing microspheres for interstitial radiosensitization of malignant glioma. Future developments concerning these microspheres for treatment of brain tumors are presented.

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Author information

Authors and Affiliations

  1. Department of Neurosurgery, Universitaire d’Angers, Angers Cedex, France

    P. Menei

  2. INSERM ERIT-M 0104 Centre Hospitalo, Universitaire d’Angers, Angers Cedex, France

    J. -P. Benoit

Authors
  1. P. Menei
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  2. J. -P. Benoit
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Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Neurochirurgie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

    M. Westphal

  2. Neurochirurgische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, München, Germany

    J.-C. Tonn

  3. Department of Neurosurgery, Tel Aviv Medical Center, Tel Aviv, Israel

    Z. Ram

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© 2003 Springer-Verlag/Wien

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Menei, P., Benoit, J.P. (2003). Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma. In: Westphal, M., Tonn, JC., Ram, Z. (eds) Local Therapies for Glioma Present Status and Future Developments. Acta Neurochirurgica Supplements, vol 88. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6090-9_9

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  • DOI: https://doi.org/10.1007/978-3-7091-6090-9_9

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-40355-6

  • Online ISBN: 978-3-7091-6090-9

  • eBook Packages: Springer Book Archive

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