Abstract
The quality of liposomes is highly dependent on their starting materials. The characteristics of liposomal formulations, including particle size, entrapment efficiency, polydispersity index, morphology, zeta potential, stability, release of drugs from liposomes, etc., is crucial for their therapeutic efficacy. Techniques and methods to measure the characteristics of liposomal formulations have their own pros and cons, and thus on basis of the properties of liposomal formulation, a suitable method for measurement should be adopted. In addition to their in vitro characterization, in vivo studies are essential to evaluate their biological behaviors, such as pharmacology, pharmacokinetics, therapeutic efficacy, safety, and toxicity study, which provides detailed information about the quality of liposomes.
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Lin, M., Wang, R., Qi, XR. (2021). Quality Evaluation of Drug-Loaded Liposomes. In: Lu, WL., Qi, XR. (eds) Liposome-Based Drug Delivery Systems. Biomaterial Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49320-5_25
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DOI: https://doi.org/10.1007/978-3-662-49320-5_25
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