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TLS-CHOP and the Role of RNA-Binding Proteins in Oncogenic Transformation

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Chromosomal Translocations and Oncogenic Transcription Factors

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 220))

Abstract

Many of the genes found to be altered in cancer cells encode proteins with regulatory effects on the pattern of gene expression. Some, like growth factor receptors and adapter molecules, do so indirectly by interfering with signaling pathways that eventually converge on a nuclear target. Others are more directly associated with regulation of gene expressions, being either DNA-binding transcription factors or proximate regulators of transcription factor function.

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Authors and Affiliations

  1. Skirball Institute of Biomolecular Medicine, Departments of Medicine and Cell Biology and the Kaplan Cancer Center, New York University Medical Center, New York, NY, 10016, USA

    D. Ron

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  1. D. Ron
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Editor information

Editors and Affiliations

  1. The Wistar Institute, 3601 Spruce Street, 19104-4268, Philadelphia, Pennsylvania, USA

    Frank J. Rauscher III Ph.D. (Associate Professor Chair, Molecular Genetics Program) (Associate Professor Chair, Molecular Genetics Program)

  2. Division of Oncovirology, BCC 239 Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, 92037, La Jolla, California, USA

    Peter K. Vogt Ph.D.

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© 1997 Springer-Verlag Berlin Heidelberg

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Ron, D. (1997). TLS-CHOP and the Role of RNA-Binding Proteins in Oncogenic Transformation. In: Rauscher, F.J., Vogt, P.K. (eds) Chromosomal Translocations and Oncogenic Transcription Factors. Current Topics in Microbiology and Immunology, vol 220. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60479-9_8

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  • DOI: https://doi.org/10.1007/978-3-642-60479-9_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64424-5

  • Online ISBN: 978-3-642-60479-9

  • eBook Packages: Springer Book Archive

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