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Magnetoencephalography pp 849–874Cite as

Review of Schizophrenia Research Using MEG

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Abstract

Schizophrenia is a severe form of mental illness characterized by hallucinations, delusions, changes in affect and serious cognitive and social dysfunction. MEG has made contributions to our understanding of the disorder in many areas, although the most significant contributions have been in four areas. First, MEG has suggested that schizophrenia may be characterized by alteration in cerebral lateralization, particularly in auditory evoked responses. Second, auditory evoked responses suggest significant impairment in early auditory perceptual processes. Third, in one of these sensory deficits in particular, the underlying source configuration of sensory gating abnormalities has provided us with information about the localization of the deficit that was not apparent from EEG studies. Finally, spectrotemporal abnormalities are evident in the disorder, particularly for low frequency oscillations, and MEG has contributed to our understanding of the regional distribution of those anomalies. These and other interesting, but less well characterized electrophysiological phenomena studied using MEG methods in schizophrenia and related psychopathologies, are reviewed in this chapter.

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Authors and Affiliations

  1. University of Colorado Denver, Anschutz Medical Campus, Denver, USA

    Donald C. Rojas

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  1. Donald C. Rojas
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Correspondence to Donald C. Rojas .

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  1. Faculty of Science Dep. of Physics, University of Zagreb, Zagreb, Croatia

    Selma Supek

  2. School of Medicine Department of Radiology, University of New Mexico, Albuquerque, USA

    Cheryl J. Aine

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Rojas, D.C. (2014). Review of Schizophrenia Research Using MEG. In: Supek, S., Aine, C. (eds) Magnetoencephalography. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-33045-2_41

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  • DOI: https://doi.org/10.1007/978-3-642-33045-2_41

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