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Micromechanics of 3D Crystallized Protein Structures

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Advances in Soft Matter Mechanics

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Abstract

In this chapter we develop micromechanics-based models of three-dimensional crystallized protein molecules with tetragonal lysozyme as an example system. While certain crystallographic directions exhibit purely elastic behavior, others exhibit elastoplastic response. The yield stress and critical resolved shear stress are observed to be sensitive to temperature and the amount of intracrystalline water. An increase in temperature and the amount of intracrystalline water molecules leads to a decrease in the critical resolved shear stress of the slip systems and makes the crystal softer. The analysis presented here may be applied to other protein crystal systems as well.

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Authors and Affiliations

  1. Advanced Computational Research Laboratory, Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, 110 8th St., Troy, NY, 12180, USA

    Amir Reza Zamiri & Suvranu De

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  1. Amir Reza Zamiri
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  2. Suvranu De
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© 2012 Higher Education Press, Beijing and Springer-Verlag Berlin Heidelberg

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Zamiri, A.R., De, S. (2012). Micromechanics of 3D Crystallized Protein Structures. In: Advances in Soft Matter Mechanics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19373-6_7

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