Abstract
The ovary is a dynamic organ, because of continuous processes of cell proliferation and regression. They are intense in the reproductive period characterized by the cyclic formation of the mature follicle, and its rupture as well as the development, maintenance and disappearance of the corpus luteum (CL; Oktem and Oktay 2008).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Adashi EY (1994) Endocrinology of the ovary. Hum Reprod 9:815–827
Adashi EY, Leung PCK (eds) (1993) The ovary. Raven, New York
Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392:245–252
Berisha B, Schams D (2005) Ovarian function in ruminants. Domest Anim Endocrinol 29:305–317
Best CL, Pudney J, Welch WR, Burger N, Hill JA (1996) Localization and characterization of white blood cell populations within the the human ovary throughout the menstrual cycle and menopause. Hum Reprod 11:790–797
Bianchi ME (2007) DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 81:1–5
Brännström M, Enskog A (2002) Leukocyte networks and ovulation. J Reprod Immunol 57:47–60
Brännström M, Norman RJ, Seamark RF, Robertson SA (1994a) Rat ovary produces cytokines during ovulation. Biol Reprod 50:88–94
Brännström M, Pascoe V, Norman RJ, McClure N (1994b) Localization of leukocyte subsets in the follicle wall and in the corpus luteum. Fertil Steril 61:488–495
Craig J, Orisaka M, Wang H, Orisaka S, Thompson W, Zhu C, Kotsuji F, Tsang BK (2007) Gonadotropin and intra-ovarian signals regulating follicle development and atresia: the delicate balance between life and death. Front Biosci 12:3628–3639
Del Canto F, Sierralta W, Kohen P, Munoz A, Strauss JF 3rd, Devoto L (2007) Features of natural and gonadotropin-releasing hormone antagonist-induced corpus. J Clin Endocrinol Metab 92:4436–4443
Devoto L, Fuentes A, Kohen P, Cespedes P, Palomino A, Pommer R, Munoz A, Strauss JF 3rd (2009) The human corpus luteum: life cycle and function in natural cycles. Fertil Steril 92:1067–1079
Espey LL (1994) Current status of the hypothesis that mammalian ovulation is comparable to an inflammatory reaction. Biol Reprod 50:233–238
Espey LL (2006) Comprehensive analysis of ovarian gene expression during ovulation using differential display. Methods Mol Biol 317:219–241
Ferguson TA, Green DR, Griffith TS (2002) Cell death and immune privilege. Int Rev Immunol 21:153–172
Foell D, Wittkowski H, Vogl T, Roth J (2007) S100 proteins expressed in phagocytes: a novel group of damage-associated molecular pattern molecules. J Leukoc Biol 81:28–37
Fraser HM, Duncan WC (2005) Vascular morphogenesis in the primate ovary. Angiogenesis 8:101–116
Fraser HM, Wulff C (2001) Angiogenesis in the primate ovary. Reprod Fertil Dev 13:557–566
Fraser HM, Wulff C (2003) Angiogenesis in the corpus luteum. Reprod Biol Endocrinol 1:88
Gougeon A (1993) Dynamics of human follicular growth: a morphologic perspective. In: Adashi EY, Leung PCK (eds) The ovary. Raven, New York, pp 21–39
Horne AW, Stock SJ, King AE (2008) Innate immunity and disorders of the female reproductive tract. Reproduction 135:739–749
Hussein MR (2005) Apoptosis in the ovary: molecular mechanisms. Hum Reprod Update 11:162–177
Iwasaki A, Medzhitov R (2010) Regulation of adaptive immunity by the innate immune system. Science 327:291–295
Keller M, Ruegg A, Werner S, Beer HD (2008) Active caspase-1 is a regulator of unconventional protein secretion. Cell 132:818–831
Kim J, Bagchi IC, Bagchi MK (2009) Signaling by hypoxia-inducible factors is critical for ovulation in mice. Endocrinology 150:3392–3400
Klune JR, Dhupar R, Cardinal J, Billiar TR, Tsung A (2008) HMGB1: endogenous danger signaling. Mol Med 14:476–484
Krohn PL (1977) Transplantation of the ovary. In: Zuckerman S, Weir B (eds) The ovary, vol 2. Acadmic, New York, pp 101–127
Liu Z, Shimada M, Richards JS (2008) The involvement of the Toll-like receptor family in ovulation. J Assist Reprod Genet 25:223–228
Matsuda-Minehata F, Inoue N, Goto Y, Manabe N (2006) The regulation of ovarian granulosa cell death by pro- and anti-apoptotic. J Reprod Dev 52:695–705
Matzinger P (2002) The danger model: a renewed sense of self. Science 296:301–305
Matzinger P (2007) Friendly and dangerous signals: is the tissue in control? Nat Immunol 8:11–13
Mayer G (2009) Innate (non-specific) immunity. Immunology – chapter one. In: University of South Carolina (ed) Microbiology and immunology textbook, pp 1–10
Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454:428–435
Medzhitov R (2010a) Inflammation 2010: new adventures of an old flame. Cell 140:771–776
Mellman I, Steinman RM (2001) Dendritic cells: specialized and regulated antigen processing machines. Cell 106:255–258
Munitz A, Levi-Schaffer F (2004) Eosinophils: ‘new’ roles for ‘old’ cells. Allergy 59:268–275
Niederkorn JY (2006) See no evil, hear no evil, do no evil: the lessons of immune privilege. Nat Immunol 7:354–359
Nishimura R, Okuda K (2010) Hypoxia is important for establishing vascularisation during corpus luteum formation in cattle. J Reprod Dev 56:110–116
Niswender GD, Juengel JL, Silva PJ, Rollyson MK, McIntush EW (2000) Mechanisms controlling the function and life span of the corpus luteum. Physiol Rev 80:1–29
Oktem O, Oktay K (2008) The ovary: anatomy and function throughout human life. Ann NY Acad Sci 1127:1–9
O'Neill LA (2008) The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress. Immunol Rev 226:10–18
O'Neill LA, Bowie AG (2007) The family of five: TIR-domain-containing adaptors in Toll-like receptor. Nat Rev Immunol 7:353–364
Paterson HM, Murphy TJ, Purcell EJ, Shelley O, Kriynovich SJ, Lien E, Mannick JA, Lederer JA (2003) Injury primes the innate immune system for enhanced Toll-like receptor reactivity. J Immunol 171:1473–1483
Peng Y, Martin DA, Kenkel J, Zhang K, Ogden CA, Elkon KB (2007) Innate and adaptive immune response to apoptotic cells. J Autoimmun 29:303–309
Peters KG, Kontos CD, Lin PC, Wong AL, Rao P, Huang L, Dewhirst MW, Sankar S (2004) Functional significance of Tie2 signaling in the adult vasculature. Recent Prog Horm Res 59:51–71
Reynolds LP, Grazul-Bilska AT, Redmer DA (2000) Angiogenesis in the corpus luteum. Endocrine 12:1–9
Richards JS, Russell DL, Ochsner S, Espey LL (2002) Ovulation: new dimensions and new regulators of the inflammatory-like response. Annu Rev Physiol 64:69–92
Richards JS, Liu Z, Shimada M (2008) Immune-like mechanisms in ovulation. Trends Endocrinol Metab 19:191–196
Rock KL, Latz E, Ontiveros F, Kono H (2010) The sterile inflammatory response. Annu Rev Immunol 28:321–342
Rohm F, Spanel-Borowski K, Eichler W, Aust G (2002) Correlation between expression of selectins and migration of eosinophils into the bovine ovary during the periovulatory period. Cell Tissue Res 309:313–322
Sandri S, Rodriguez D, Gomes E, Monteiro HP, Russo M, Campa A (2008) Is serum amyloid A an endogenous TLR4 agonist? J Leukoc Biol 83:1174–1180
Schams D, Berisha B (2004) Regulation of corpus luteum function in cattle – an overview. Reprod Domest Anim 39:241–251
Serke H, Vilser H, Nowicki M, Hmeidan FA, Blumenauer V, Hummitzsch K, Lösche A, Spanel-Borowski K (2009) Granulosa cell subtypes respond by autophagy or cell death to oxLDL-dependent activation of the oxidized lipoprotein receptor 1 and toll-like 4 receptor. Autophagy 5:991–1003
Shimada M, Yanai Y, Okazaki T, Noma N, Kawashima I, Mori T, Richards JS (2008) Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization. Development 135:2001–2011
Spanel-Borowski K, Thor-Wiedemann S, Pilgrim C (1984) Cell proliferation in the dog (beagle) ovary during proestrus and early estrus. Acta Anat (Basel) 118:153–158
Steinman RM, Banchereau J (2007) Taking dendritic cells into medicine. Nature 449:419–426
Stocco C, Telleria C, Gibori G (2007) The molecular control of corpus luteum formation, function, and regression. Endocr Rev 28:117–149
Stouffer RL, Xu F, Duffy DM (2007) Molecular control of ovulation and luteinization in the primate follicle. Front Biosci 12:297–307
Takeda K, Akira S (2005) Toll-like receptors in innate immunity. Int Immunol 17:1–14
Takeuchi O, Akira S (2010) Pattern recognition receptors and inflammation. Cell 140:805–820
Tsung A, Zheng N, Jeyabalan G, Izuishi K, Klune JR, Geller DA, Lotze MT, Lu L, Billiar TR (2007) Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury. J Leukoc Biol 81:119–128
Turvey SE, Broide DH (2010) Innate immunity. J Allergy Clin Immunol 125:S24–32
van Lierop PPE, Samsom JN, Escher JC, Nieuwenhuis EE (2009) Role of the innate immune system in the pathogenesis of inflammatory bowel disease. J Pediatr Gastroenterol Nutr 48:142–151
Van Wenzel IL, Dharmarajan AM, Lavranos TC, Rodgers RJ (1999) Evidence for alternative pathways of granulosa cell death in healthy and slightly. Endocrinology 140:2602–2612
Wu R, van der Hoek KH, Ryan NK, Norman RJ, Robker RL (2004) Macrophage contributions to ovarian function. Hum Reprod Update 10:119–133
Zeleznik AJ (1993) Dynamics of primate follicular growth: a physiologic perspective. In: Adashi EY, Leung PCK (eds) The ovary. Raven, New York, pp 41–55
Zhan R, Leng X, Liu X, Wang X, Gong J, Yan L, Wang L, Wang Y, Wang X, Qian LJ (2009) Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes. Biochem Biophys Res Commun 387:229–233
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2011 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Spanel-Borowski, K. (2011). Background. In: Footmarks of Innate Immunity in the Ovary and Cytokeratin-Positive Cells as Potential Dendritic Cells. Advances in Anatomy, Embryology and Cell Biology, vol 209. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16077-6_1
Download citation
DOI: https://doi.org/10.1007/978-3-642-16077-6_1
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-16076-9
Online ISBN: 978-3-642-16077-6
eBook Packages: MedicineMedicine (R0)