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Entomopathogenic Fungi: Biochemistry and Molecular Biology

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Human and Animal Relationships

Part of the book series: The Mycota ((MYCOTA,volume 6))

Entomopathogenic fungi (EPF) have become a significant force in shaping the larger context of insecticides within contemporary insect pest management schemes (Lord 2005; Roy et al., 2006; Khachatourians 2008). Needless to say, as mycologists we need the perspective and understanding to explain the diversity of EPF and their spatial and temporal distribution within the insect ecosystem. In the past decade, the accelerated focus of research and scholarly studies has generated two perspectives: (a) the molecular biology, genomics and proteomics of EPF, and (b) the practical use of EPF in insect pest management schemes. Their value therefore is two-fold, first in the study of microbial pathogenicity and second in their application to the microbial control of phytophagous insects as much as biting and hematophagous insect pest populations. Altogether some 90 genera and 700 species are involved with entomopathogenicity, only a few members of the Entomophthorales and Hyphomycetes have been well studied. In the past decade, major new developments in the realm of application of the knowledge of EPF to insect pest management have been realized (Khachatourians 1996). New developments in genomic and molecular research and serious interest in commercialization of EPF for pest control have become the new drivers of understanding in the field, challenges that were forecasted to meet the promise of new biotechnology (Khachatourians 1986). With such knowledge, physiological manipulations, isolation of mutants with enhanced virulence, and construction of environmentally safe strains with limited persistence should be possible within the near future. This chapter primarily reviews the literature since 1995 on the biochemistry and molecular biology of EPF and their involvement in the disease of insects. Additional sources of information can be followed from Table 3.1.

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Khachatourians, G.G., Qazi, S.S. (2008). Entomopathogenic Fungi: Biochemistry and Molecular Biology. In: Brakhage, A.A., Zipfel, P.F. (eds) Human and Animal Relationships. The Mycota, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-79307-6_3

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