Skip to main content

Mining Acute Stroke Patients’ Data Using Supervised Machine Learning

  • Conference paper
  • First Online:
Mathematical Aspects of Computer and Information Sciences (MACIS 2017)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 10693))

Abstract

Analysis of data for identifying patterns and building models has been used as a strong tool in different domains, including medical domains. In this paper, we analyse the registry of brain stroke patients collected over fifteen years in south London hospitals, known as South London Stroke Register. Our attempt is to identify the similar patterns between patients’ background and living conditions, their cognitive ability, the treatments they received, and the speed of their cognitive recovery; based on which most effective treatment can be predicted for new admitted patients. We designed a novel strategy which takes into account two different approaches. First is to predict, for each of the potential intervention treatments, whether that particular treatment would lead to recovery of a new patient or not. Second is to suggest a treatment (treatments) for the patient based on those that were given to the patients who have recovered and are most similar to the new patient. We built different classifiers using various state of the art machine learning algorithms. These algorithms were evaluated and compared based on three performance metrics, defined in this paper. Given that time is very crucial for stroke patients, main motivation of this research work is identifying the most effective treatment immediately for a new patient, and potentially increase the probability of their cognitive recovery.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    details can be found online at: KCL Faculty of Life Sciences and Medicine, Stroke re search group.

  2. 2.

    For this study Weka 3.6.11 has been used.

References

  1. State of the Nation: stroke statistics. Stroke Association, January 2015. http://www.stroke.org.uk/

  2. Strokes rising among people of working age, warns charity. BBC Health news, March 2015. http://www.bbc.com/news/health-32690040

  3. Aha, D., Kibler, D.: Instance-based learning algorithms. Mach. Learn. 6, 37–66 (1991)

    MATH  Google Scholar 

  4. Asadi, H., Dowling, R., Yan, B., Mitchell, P.: Machine learning for outcome prediction of acute ischemic stroke post intra-arterial therapy. PLoS ONE 9 (2014). https://doi.org/10.1371/journal.pone.0088225

  5. Ben-David, A.: Comparison of classification accuracy using cohen’s weighted kappa. Expert Syst. Appl. 34(2), 82–832 (2009)

    Google Scholar 

  6. Bentley, P., Ganesalingam, J., Jones, A.L.C., Mahady, K., Epton, S., Rinne, P., Sharma, P., Halse, O., Mehta, A., Rueckert, D.: Prediction of stroke thrombolysis outcome using CT brain machine learning. NeuroImage Clin. 4, 635–640 (2014)

    Article  Google Scholar 

  7. Bouts, M.J., Tiebosch, I.A., van der Toorn, A., Viergever, M.A., Wu, O., Dijkhuizen, R.M.: Early identification of potentially salvageable tissue with MRI-based predictive algorithms after experimental ischemic stroke. J. Cereb. Blood Flow Metab. 33(7), 1075–1082 (2013)

    Article  Google Scholar 

  8. Cleary, J.G., Trigg, L.E.: K*: An instance-based learner using an entropic distance measure. In: 12th International Conference on Machine Learning, pp. 108–114 (1995)

    Google Scholar 

  9. Cuingnet, R., Rosso, C., Lehéricy, S., Dormont, D., Benali, H., Samson, Y., Colliot, O.: Spatially regularized SVM for the detection of brain areas associated with stroke outcome. In: Jiang, T., Navab, N., Pluim, J.P.W., Viergever, M.A. (eds.) MICCAI 2010. LNCS, vol. 6361, pp. 316–323. Springer, Heidelberg (2010). https://doi.org/10.1007/978-3-642-15705-9_39

    Chapter  Google Scholar 

  10. Fawcett, T.: An introduction to ROC analysis. Pattern Recogn. Lett. 14(27), 861–874 (2006)

    Article  Google Scholar 

  11. Folstein, M.F., Folstein, S.E., McHugh, P.R.: Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J. Psychiatr. Res. 12(3), 189–198 (1975)

    Article  Google Scholar 

  12. Freund, Y., Mason, L.: The alternating decision tree learning algorithm. In: Proceeding of the Sixteenth International Conference on Machine Learning, Bled, Slovenia, pp. 124–133 (1999)

    Google Scholar 

  13. Hall, M., Frank, E., Holmes, G., Pfahringer, B., Reutemann, P., Witten, I.H.: The weka data mining software: An update. SIGKDD Explor. 11(1), 385–403 (2009)

    Article  Google Scholar 

  14. Har-Peled S., Roth, D., Zimak, D.: Constraint classification for multiclass classification and ranking. In: 16th Annual Conference on Neural Information Processing Systems, NIPS-02, pp. 785–792. MIT Press (2003)

    Google Scholar 

  15. Hodkinson, H.M.: Evaluation of a mental test score for assessment of mental impairment in the elderly. Age Ageing 1(4), 233–238 (1972)

    Article  Google Scholar 

  16. John, G.H., Langley, P.: Estimating continuous distributions in bayesian classifiers. In: Eleventh Conference on Uncertainty in Artificial Intelligence, pp. 338–345. Morgan Kaufmann, San Mateo (1995)

    Google Scholar 

  17. Kecman, V.: Learning and Soft Computing: Support Vector Machines, Neural Networks and Fuzzy Logic Systems. MIT Press, Cambridge (2001)

    MATH  Google Scholar 

  18. Kohavi, R.: The power of decision tables. In: Lavrac, N., Wrobel, S. (eds.) ECML 1995. LNCS, vol. 912, pp. 174–189. Springer, Heidelberg (1995). https://doi.org/10.1007/3-540-59286-5_57

    Google Scholar 

  19. Kohavi, R.: A study of cross-validation and bootstrap for accuracy estimation and model selection. In: Proceeding of 14th International Joint Conference on Artificial Intelligence, (IJCAI 1995), pp. 1137–1143 (1995)

    Google Scholar 

  20. Kohavi, R.: Scaling up the accuracy of naive-bayes classifiers: A decision-tree hybrid. In: Second International Conference on Knowledge Discovery and Data Mining, pp. 202–207 (1996)

    Google Scholar 

  21. Quinlan, R.: C4.5: Programs for Machine Learning. Morgan Kaufmann Publishers, San Mateo (1993)

    Google Scholar 

  22. Rumelhart, D.E., Hinton, G.E., Williams, R.J.: Learning internal representations by error propagation. In: Parallel Distributed Processing: Explorations in the Microstructure of Cognition, vol. 1, pp. 318–362. MIT Press (1986)

    Google Scholar 

  23. Varma, S., Simon, R.: Bias in error estimation when using cross-validation for model selection. BMC Bioinformatics 7(91) (2006)

    Google Scholar 

  24. Warwick, K.: March of the Machines: The Breakthrough in Artificial Intelligence. University of Illinois Press, Champaign (2004)

    Google Scholar 

  25. Wolfe, C.D., Crichton, S.L., Heuschmann, P.U., McKevitt, C.J., Toschke, A.M., Grieve, A.P., Rudd, A.G.: Estimates of outcomes up to ten years after stroke: analysis from the prospective South London stroke register. PLoS Med. 8(5) (2011)

    Google Scholar 

Download references

Acknowledgement

The authors would like to thank Miss Siobhan Crichton from the department of Primary Care & Public Health Sciences at King’s College for providing support on the dataset, to the authors. Also, we would like to thank Dr. Arshia Sedigh at King’s College Hospital for his valuable advice on understanding the data without which this work was not possible.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ritu Kundu .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer International Publishing AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Kundu, R., Mahmoodi, T. (2017). Mining Acute Stroke Patients’ Data Using Supervised Machine Learning. In: Blömer, J., Kotsireas, I., Kutsia, T., Simos, D. (eds) Mathematical Aspects of Computer and Information Sciences. MACIS 2017. Lecture Notes in Computer Science(), vol 10693. Springer, Cham. https://doi.org/10.1007/978-3-319-72453-9_30

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-72453-9_30

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-72452-2

  • Online ISBN: 978-3-319-72453-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics