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Gastroparesis, Postprandial Distress

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Gastrointestinal Motility Disorders

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Abstract

Gastroparesis is a chronic symptomatic disorder of the stomach characterized by delayed emptying without evidence of mechanical obstruction. Symptoms from gastroparesis include nausea, vomiting, early satiety, postprandial fullness, and, in some patients, upper abdominal pain. The three main causes of gastroparesis are diabetic, postsurgical, and idiopathic. Management of gastroparesis includes assessment and correction of dehydration and malnutrition if present, maintaining nutritional intake, relief of symptoms, improvement of gastric emptying, and, in diabetics, glycemic control. Diet and nutrition should be managed by oral dietary modifications such as smaller meals, low-fat-containing meals, low-roughage-containing meals. Medical treatment entails use of prokinetic and antiemetic therapies. For refractory cases, jejunostomy feeding tube, gastric electric stimulator, and pyloromyotomy may need to be considered. Unfortunately, current approved treatment options do not adequately address clinical need. Attention should be given to the development of new effective therapies for symptomatic control.

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Authors and Affiliations

  1. Gastroenterology Section, Temple University School of Medicine, Philadelphia, PA, USA

    Henry P. Parkman M.D.

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  1. Henry P. Parkman M.D.
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Correspondence to Henry P. Parkman M.D. .

Editor information

Editors and Affiliations

  1. Institute of Gastroenterology, Sheba medical Center, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel

    Eytan Bardan

  2. Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA

    Reza Shaker

Additional information

A book chapter for “Gastrointestinal Motility Disorders: A Point-of-Care Clinical Guide”. Editors: Eytan Bardan, MD and Reza Shaker, MD.

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Parkman, H.P. (2018). Gastroparesis, Postprandial Distress. In: Bardan, E., Shaker, R. (eds) Gastrointestinal Motility Disorders . Springer, Cham. https://doi.org/10.1007/978-3-319-59352-4_24

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  • DOI: https://doi.org/10.1007/978-3-319-59352-4_24

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