Abstract
Magnetic resonance imaging (MRI) is a medical technique used in radiology to obtain anatomical images of healthy and pathological tissues. Due to hardware limitations and clinical protocols, MRI data are often acquired with low-resolution. For this reason, the scientific community has been developing super-resolution (SR) methodologies in order to enhance spatial resolution through post-processing of 2D multi-slice images. The enhancement of spatial resolution in magnetic resonance (MR) images improves clinical procedures such as tissue segmentation, registration and disease diagnosis. Several methods to perform SR-MR images have been proposed. However, they present different drawbacks: sensitivity to noise, high computational cost, and complex optimization algorithms. In this paper, we develop a supervised learning methodology to perform SR-MR images using a patch-based Gaussian process regression (GPR) method. We compare our approach with nearest-neighbor interpolation, B-splines and a SR-GPR scheme based on nearest-neighbors. We test our SR-GPR algorithm in MRI-T1 and MRI-T2 studies, evaluating the performance through error metrics and morphological validation (tissue segmentation). Results obtained with our methodology outperform the other alternatives for all validation protocols.
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Acknowledgments
H.D. Vargas Cardona is funded by Colciencias under the program: formación de alto nivel para la ciencia, la tecnología y la innovación - Convocatoria 617 de 2013. This research has been developed under the project: Estimación de los parámetros de neuro modulación con terapia de estimulación cerebral profunda en pacientes con enfermedad de Parkinson a partir del volumen de tejido activo planeado, financed by Colciencias with code 1110-657-40687.
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Cardona, H.D.V., López-Lopera, A.F., Orozco, Á.A., Álvarez, M.A., Tamames, J.A.H., Malpica, N. (2015). Gaussian Processes for Slice-Based Super-Resolution MR Images. In: Bebis, G., et al. Advances in Visual Computing. ISVC 2015. Lecture Notes in Computer Science(), vol 9475. Springer, Cham. https://doi.org/10.1007/978-3-319-27863-6_65
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DOI: https://doi.org/10.1007/978-3-319-27863-6_65
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