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Pediatric Hydrocephalus pp 1065–1081Cite as

Hydrocephalus in Achondroplasia and Venous Hypertension

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Abstract

The cause of hydrocephalus in achondroplasia is believed to be chronic venous hypertension, which in turn, is due to the anomalous neuroanatomy associated with this disorder. The venous anatomy in achondroplasia is now known to undergo substantial compensation during development, which could partly account for the benign nature of hydrocephalus in this population. The management is controversial, owing to inadequate understanding of the natural history and pathophysiology of this condition. This chapter recapitulates our current understanding of hydrocephalus in achondroplasia, with special emphasis on the role of venous hypertension, its impact on CSF circulation and management of hydrocephalus.

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Author information

Authors and Affiliations

  1. Pediatric Neurosurgery, British Columbia Children’s Hospital and the University of British Columbia, Vancouver, BC, Canada

    Sudheesh Ramachandran

  2. Division of Pediatric Neurosurgery, Department of Surgery British Columbia Children’s Hospital and the University of British Columbia, Vancouver, BC, Canada

    Paul Steinbok

Authors
  1. Sudheesh Ramachandran
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  2. Paul Steinbok
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Corresponding author

Correspondence to Paul Steinbok .

Editor information

Editors and Affiliations

  1. Pediatric Neurosurgery, Santobono Pausilipon Children’s Hospital, Naples, Italy

    Giuseppe Cinalli

  2. Division of Pediatric Neurosurgery, Acıbadem University, School of Medicine, Istanbul, Turkey

    M. Memet Özek

  3. Pediatric Neurosurgery, Hôpital Necker-Enfants Malades Université René Descartes-Paris V, Paris, France

    Christian Sainte-Rose

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Ramachandran, S., Steinbok, P. (2019). Hydrocephalus in Achondroplasia and Venous Hypertension. In: Cinalli, G., Özek, M., Sainte-Rose, C. (eds) Pediatric Hydrocephalus. Springer, Cham. https://doi.org/10.1007/978-3-319-27250-4_63

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  • DOI: https://doi.org/10.1007/978-3-319-27250-4_63

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-27248-1

  • Online ISBN: 978-3-319-27250-4

  • eBook Packages: MedicineReference Module Medicine

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