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A Two-Color Interacting Random Balls Model for Co-localization Analysis of Proteins

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Geometric Science of Information (GSI 2015)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 9389))

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Abstract

A model of two-type (or two-color) interacting random balls is introduced. Each colored random set is a union of random balls and the interaction relies on the volume of the intersection between the two random sets. This model is motivated by the detection and quantification of co-localization between two proteins. Simulation and inference are discussed. Since all individual balls cannot been identified, e.g. a ball may contain another one, standard methods of inference as likelihood or pseudolikelihood are not available and we apply the Takacs-Fiksel method with a specific choice of test functions.

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Correspondence to F. Lavancier .

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Lavancier, F., Kervrann, C. (2015). A Two-Color Interacting Random Balls Model for Co-localization Analysis of Proteins. In: Nielsen, F., Barbaresco, F. (eds) Geometric Science of Information. GSI 2015. Lecture Notes in Computer Science(), vol 9389. Springer, Cham. https://doi.org/10.1007/978-3-319-25040-3_20

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  • DOI: https://doi.org/10.1007/978-3-319-25040-3_20

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-25039-7

  • Online ISBN: 978-3-319-25040-3

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