Abstract
Small vessel disease (SVD) refers to all pathological processes that affect the small vessels of the brain. SVD is an important cause of acute stroke, but is also a leading cause of aging-related cognitive decline and dementia, due to more insidious brain parenchymal damage. The introduction of high field strength MRI (7 T) is likely to offer important new perspectives on the role of SVD in these disorders. In this overview we illustrate the opportunities that 7 T MRI offers in high resolution vascular imaging. In particular, we will show the capability of 7 T MRI to depict the small arteries and veins in the brain, the vascular wall of intracranial arteries, perivascular spaces, and microvascular parenchymal lesions, including microbleeds and microinfarcts.
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Acknowledgements
This project was supported by a VIDI grant from ZonMw, The Netherlands Organization for Health Research and Development [Grant # 91711384], and a grant from the Netherlands Heart Foundation [Grant # 2010T073] to GJB.
Conflict of Interest
Prof. Luijten receives research support from Philips Health Care.
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van Veluw, S.J., Zwanenburg, J.J.M., Hendrikse, J., van der Kolk, A.G., Luijten, P.R., Biessels, G.J. (2014). High Resolution Imaging of Cerebral Small Vessel Disease with 7 T MRI. In: Tsukahara, T., Esposito, G., Steiger, HJ., Rinkel, G., Regli, L. (eds) Trends in Neurovascular Interventions. Acta Neurochirurgica Supplement, vol 119. Springer, Cham. https://doi.org/10.1007/978-3-319-02411-0_21
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DOI: https://doi.org/10.1007/978-3-319-02411-0_21
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