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Sex chromosomes and sex-determining genes: insights from marsupials and monotremes

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Genes and Mechanisms in Vertebrate Sex Determination

Part of the book series: Experientia Supplementum ((EXS,volume 91))

Summary

Comparative studies of the genes involved in sex determination in the three extant classes of mammals, and other vertebrates, has allowed us to identify genes that are highly conserved in vertebrate sex determination and those that have recently evolved roles in one lineage. Analysis of the conservation and function of candidate sex determining genes in marsupials and monotremes has been crucial to our understanding of their function and positioning in a conserved mammalian sex-determining pathway, as well as their evolution. Here we review comparisons between genes in the sex-determining pathway in different vertebrates, and ask how these comparisons affect our views on the role of each gene in vertebrate sex determination.

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Authors and Affiliations

  1. Department of Zoology, The University of Melbourne, Parkville, Vic, 3052, Australia

    Andrew Pask

  2. School of Genetics and Evolution, La Trobe University, Melbourne, Vic, 3083, Australia

    Jennifer A. Marshall Graves

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  1. Andrew Pask
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  2. Jennifer A. Marshall Graves
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Editors and Affiliations

  1. Institute of Human Genetics and Anthropology, University of Freiburg, Breisacher Strasse 33, 79106, Freiburg, Germany

    Gerd Scherer

  2. Department of Human Genetics, University of WĂĽrzburg, Biozentrum Am Hubland, 97074, WĂĽrzburg, Germany

    Michael Schmid

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Pask, A., Graves, J.A.M. (2001). Sex chromosomes and sex-determining genes: insights from marsupials and monotremes. In: Scherer, G., Schmid, M. (eds) Genes and Mechanisms in Vertebrate Sex Determination. Experientia Supplementum, vol 91. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-7781-7_5

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  • DOI: https://doi.org/10.1007/978-3-0348-7781-7_5

  • Publisher Name: Birkhäuser, Basel

  • Print ISBN: 978-3-0348-7783-1

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