Abstract
Since bioresorbable metal alloys like magnesium and iron are highly interesting in biomedical applications , significant efforts have been made to decrease the degradation rate of magnesium alloys, as well as to increase the degradation rate of iron-based alloys . Since silver is known to act as an effective cathode for iron, in addition to its antibacterial behaviour, it is gaining more interest as an alloying element for iron. Unfortunately, silver itself corrodes extremely slowly, and the effect of silver in the nanoscale on the human organism is, up to now, still controversial. Therefore, new silver alloys based on rare earth elements, as well as on typical elements for biomedical applications (Ca, Mg, Zn) with an adapted degradation profile (rate, scale of corrosion products), are a focal point of this work. Due to the immiscibility of iron and silver, it is not possible to cast iron–silver X-alloys, but it is feasible to manufacture these alloys using powder-based additive technologies.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Peuster M, Hesse C, Schloo T, Fink C, Beerbaum P, von Schnakenburg C (2006) Long-term biocompatibility of a corrodible peripheral iron stent in the porcine descending aorta. Biomaterials 27:4955–4962
Hermawan H, Moravej M, Dubé D, Fiset M, Mantovani D (2007) Degradation behaviour of metallic biomaterials for degradable stents. Adv Mater Res 15–17:113–118
Hermawan H, Dubé D, Mantovani D (2007) Development of degradable Fe-35Mn alloy for biomedical application. Adv Mater Res 15–17:107–112
Hermawan H, Purnama A, Dube D, Couet J, Mantovani D (2010) Fe-Mn alloys for metallic biodegradable stents: degradation and cell viability studies. Acta Biomater 6:1852–1860
Hermawan H, Dube D, Mantovani D (2010) Developments in metallic biodegradable stents. Acta Biomater 6:1693–1697
Heiden M, Walker E, Nauman E, Stanciu L (2015) Evolution of novel bioresorbable iron–manganese implant surfaces and their degradation behaviors in vitro. J Biomed Mater Res Part A 103A:185–193
Drynda A, Hassel T, Fr-W Bach, Peuster M (2015) In vitro and in vivo corrosion properties of new iron–manganese alloys designed for cardiovascular applications. J Biomed Mater Res B 03:649–660
Francis A, Yang Y, Virtanen S, Boccaccini AR (2015) Iron and iron-based alloys for temporary cardiovascular applications. J Mater Sci Mater Med 26:138
Jansen B, Rinck M, Wolbring P, Strohmeier A, Jahns T (1994) In vitro evaluation of the antimicrobial efficacy and biocompatibility of a silver-coated central venous catheter. J Biomater Appl 9:55–70
Karchmer TB, Giannetta ET, Muto CA, Strain BA, Farr BM (2000) Randomized crossover study of silver-coated urinary catheters in hospitalized patients. Arch Intern Med 21:3294–3298
Huang T, Cheng J, Bian D, Zheng Y (2016) Fe-Au and Fe-Ag composites as candidates for biodegradable stent materials. J Biomed Mater Res B 104(2):225
Niendorf T, Brenne F, Hoyer P, Schwarze D, Schaper M, Grothe R, Wiesener M, Grundmeier G, Maier HJ (2015) Processing of new materials by additive manufacturing: iron-based alloys containing silver for biomedical applications. Metall Mater Trans A 46:2829–2933
Wiesener M, Peters K, Taube A, Keller A, Hoyer K-P, Niendorf T, Grundmeier G (2017) Corrosion properties of bioresorbable FeMn-Ag alloys prepared by selective laser melting. Mater Corros 68:1028–1036
ASM Alloy P D D ASM alloy phase diagram database
Murr LE, Gaytan SM, Ramirez DA, Martinez E, Hernandez J, Amato KN, Shindo PW, Medina FR, Wicker RB (2012) Metal fabrication by additive manufacturing using laser and electron beam melting technologies. J Mater Sci Technol 28:1–14
Yan C, Hao L, Hussein A, Raymont D (2012) Evaluations of cellular lattice structures manufactured using selective laser melting. Int J Mach Tools Manuf 62:32–38
Nune KC, Devesh R, Misra K, Gaytan SM, Murr LE (2014) Interplay between cellular activity and three-dimensional scaffold-cell constructs with different foam structure processed by electron beam melting. J Biomed Mater Res 103A(5):1677–1692
Acknowledgements
The authors thank Mathias von Spalden, Maik Robert Peters, and Thomas Janzen for their support during the investigations.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 The Minerals, Metals & Materials Society
About this paper
Cite this paper
Hoyer, KP., Schaper, M. (2019). Alloy Design for Biomedical Applications in Additive Manufacturing. In: TMS 2019 148th Annual Meeting & Exhibition Supplemental Proceedings. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-030-05861-6_44
Download citation
DOI: https://doi.org/10.1007/978-3-030-05861-6_44
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-05860-9
Online ISBN: 978-3-030-05861-6
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)