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Liver Stem Cells pp 11–23Cite as

Clinical Uses of Liver Stem Cells

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 826))

Abstract

Liver transplantation offers a definitive cure for many liver and metabolic diseases. However, the complex invasive procedure and paucity of donor liver graft organs limit its clinical applicability. Liver stem cells provide a potentially limitless source of cells that would be useful for a variety of clinical applications. These stem cells or hepatocytes generated from them can be used in cellular transplantation, bioartificial liver devices and drug testing in the development of new drugs. In this chapter, we review the technical aspects of clinical applications of liver stem cells and the progress made to date in the clinical setting. The difficulties and challenges of realizing the potential of these cells are discussed.

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Authors and Affiliations

  1. Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    Yock Young Dan

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  1. Yock Young Dan
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Correspondence to Yock Young Dan .

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  1. Research Inst., National Cancer Center, Tsukiji 5-1-1, Tokyo, 104-0045, Japan

    Takahiro Ochiya

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Dan, Y.Y. (2012). Clinical Uses of Liver Stem Cells. In: Ochiya, T. (eds) Liver Stem Cells. Methods in Molecular Biology, vol 826. Springer, New York, NY. https://doi.org/10.1007/978-1-61779-468-1_2

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  • DOI: https://doi.org/10.1007/978-1-61779-468-1_2

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