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Evaluation of the Asymmetric Division of Drosophila Male Germline Stem Cells

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Germline Stem Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1463))

Abstract

Asymmetric cell division (ACD) is utilized in many stem cell systems to produce two daughter cells with different cell fates. Despite the fundamental importance of ACD during development and tissue homeostasis, the nature of ACD is far from being fully understood. Step-by-step observation of events during ACD allows us to understand processes that lead to ACD. Here we describe examples of how we evaluate ACD in vivo using the Drosophila male germline stem cell system.

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Acknowledgement

The research in the Yamashita laboratory is supported by the Howard Hughes Medical Institute and the National Institute of Health (R01 GM118308). YMY is supported by the John D. and Catherine T. MacArthur Foundation.

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Authors and Affiliations

  1. Department of Cell and Developmental Biology, Life Sciences Institute, Howard Hughes Medical Institute, University of Michigan Medical School, 210 Washtenaw Ave, Ann Arbor, MI, 48105, USA

    Mayu Inaba & Yukiko M. Yamashita

  2. Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, 75390-9148, USA

    Mayu Inaba

Authors
  1. Mayu Inaba
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  2. Yukiko M. Yamashita
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Corresponding author

Correspondence to Mayu Inaba .

Editor information

Editors and Affiliations

  1. Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA

    Michael Buszczak

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Inaba, M., Yamashita, Y.M. (2017). Evaluation of the Asymmetric Division of Drosophila Male Germline Stem Cells. In: Buszczak, M. (eds) Germline Stem Cells. Methods in Molecular Biology, vol 1463. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-4017-2_3

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  • DOI: https://doi.org/10.1007/978-1-4939-4017-2_3

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-4015-8

  • Online ISBN: 978-1-4939-4017-2

  • eBook Packages: Springer Protocols

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