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Rabbit Model for Superantigen-Mediated Lethal Pulmonary Disease

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1396))

Abstract

Staphylococcus aureus is a highly significant cause of serious human infections in the USA. Many of these illnesses are mediated by interactions between the host immune system and staphylococcal superantigens (SAgs). Several of these severe staphylococcal infections are initiated in the lungs, making this an important site to study. Here, we describe the rabbit model for investigating the role of staphylococcal SAgs in pulmonary-associated lethal infection and intoxication.

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Correspondence to Kristi L. Strandberg .

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Strandberg, K.L., Rotschafer, J.H., Schlievert, P.M. (2016). Rabbit Model for Superantigen-Mediated Lethal Pulmonary Disease. In: Brosnahan, A. (eds) Superantigens. Methods in Molecular Biology, vol 1396. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3344-0_7

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  • DOI: https://doi.org/10.1007/978-1-4939-3344-0_7

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3342-6

  • Online ISBN: 978-1-4939-3344-0

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