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Human Immunodeficiency Virus

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Abstract

Patients with the human immunodeficiency virus (HIV) have a greatly increased risk of kidney disease, due in part to HIV-associated nephropathy and commonly used nephrotoxic medications. The cutaneous manifestations of HIV are a vast spectrum of disorders including exaggerated or atypical presentations of common diseases, opportunistic infections, and adverse medication reactions. A dermatologic sign or symptom may be the first presentation of an occult HIV infection. Many cutaneous manifestations of HIV are correlated with CD4 T-cell count, such that skin diseases may progress more rapidly or present in an atypical fashion as immune status deteriorates. The introduction of effective antiretroviral treatment has modified the course of the disease while simultaneously introducing its own complications including medication reactions, lipodystrophy syndrome, and the immune reconstitution syndrome.

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Abbreviations

AIDS:

Acquired immune deficiency syndrome

EF:

Eosinophilic folliculitis

FTA-ABS:

Fluorescent treponemal antibody-absorption

HAART:

Highly active antiretroviral therapy

HIV:

Human immunodeficiency virus

HLA:

Human leukocyte antigen

HPV:

Human papillomavirus

HSV:

Herpes simplex virus

IRIS:

Immune reconstitution inflammatory syndrome

KS:

Kaposi sarcoma

PCR:

Polymerase chain reaction

PPE:

Pruritic papular eruption

PUVA:

Psoralen plus ultraviolet A

RPR:

Rapid plasma reagin

UVB:

Ultraviolet B

VZV:

Varicella zoster virus

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Correspondence to Caroline Y. Winslow M.D. .

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Winslow, C.Y., Kerdel, F.A. (2015). Human Immunodeficiency Virus. In: Nunley, J., Lerma, E. (eds) Dermatological Manifestations of Kidney Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2395-3_4

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  • DOI: https://doi.org/10.1007/978-1-4939-2395-3_4

  • Publisher Name: Springer, New York, NY

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