Abstract
Generally considered a commensal organism, Enterococcus faecalis has emerged as a major nosocomial pathogen3. In addition, enterococci are acquiring resistances to every therapeutically useful antibiotic. Since previous studies had shown the enterococcal cell envelope to be a barrier to the efficient uptake of antibiotics, it was of interest to begin studies examining the molecular biology of the enterococcal cell wall5. An existing nucleotide sequence library was searched for functions potentially related to the structure and function of the enterococcal cell wall. In this study, we identified E. faecalis homologs to genes of the E. coli K-12 rfb operon (rfbA, rfb6)7, 10, which in enteric organisms are involved in LPS modification.
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Hancock, L.E., Gilmore, M.S. (1997). Identification of a Highly Conserved Lipopolysaccharide (LPS) Modification Operon in Enterococcus faecalis . In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_247
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DOI: https://doi.org/10.1007/978-1-4899-1825-3_247
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