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Streptolysin O Modulates Cytokine Synthesis in Human Peripheral Blood Mononuclear Cells

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Streptococci and the Host

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 418))

Abstract

Invasive Group A streptococcal (GAS) infections associated with bacteremia, shock, and death have been defined as the streptococcal toxic shock syndrome (StrepTSS). Strains of GAS commonly isolated from patients with StrepTSS have been M-types 1 and 3 which produce pyrogenic exotoxins (SPE’s). Epidemiological studies in the United States demonstrate pyrogenic exotoxin A (SPE A) in a high percentage of these strains; cases in Sweden have more commonly been associated with SPE B (reviewed in6).

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References

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© 1997 Springer Science+Business Media New York

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Stevens, D.L., Bryant, A.E. (1997). Streptolysin O Modulates Cytokine Synthesis in Human Peripheral Blood Mononuclear Cells. In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_217

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  • DOI: https://doi.org/10.1007/978-1-4899-1825-3_217

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1827-7

  • Online ISBN: 978-1-4899-1825-3

  • eBook Packages: Springer Book Archive

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