Abstract
One of the best established roles of taurine is that of an osmoregulator7. Many cell types have been shown to sustain a loss of taurine upon exposure to hypoosmotic stress11 while an increased uptake of this amino acid can be induced by hyperosmotic conditions12. The latter effect has been demonstrated in renal cells in culture, thus supporting the notion that taurine acts as an organic osmolyte in the kidney along with polyhydric alcohols and methylamines5.
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References
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Amiry-Moghaddam, M., Nagelhus, E.A., Agre, P., Nielsen, S., Ottersen, O.P. (1996). Taurine and Water Channels are Co-Localized in Renal Tubule Cells and Other Tissues. In: Huxtable, R.J., Azuma, J., Kuriyama, K., Nakagawa, M., Baba, A. (eds) Taurine 2. Advances in Experimental Medicine and Biology, vol 403. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-0182-8_19
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