Skip to main content

Subclinical Shedding of HSV: Its Potential for Reduction by Antiviral Therapy

  • Chapter
Antiviral Chemotherapy 4

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 394))

Abstract

Several recent serosurveys have indicated that the prevalence of HSV-2 infection is continuing to increase (Table 1)1–5. The prevalence of HSV-2 is high in many populations. In Seattle, 43% of women and 35% of men attending STD clinics have already acquired HSV-2 infection, while in British STD clinic attendees, the figures are 37% and 27%. Breinig et al reported that 21% of women attending family planning clinics were HSV-2 seropositive3. Perhaps the most definitive work in this area is a recent population based serosurvey of the US adults which has shown that the overall seroprevalence of HSV-2 has risen from 16.4% in 1978 to 21.7% in 1990; a 32% increase in HSV-2 seropositivity in the last decade6.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Nahmias M, Lee FK, Beckman-Nahmias S. Seroepidemiological and sociological patterns of herpes simplex virus infection in the world. Scand J Infect Dis Suppl 1990; 69: 19036.

    Google Scholar 

  2. Ashley R. Herpes simplex virus, In: Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections. 75h Edition, Ed: E. Lennette. Amer Public Health Assoc., Washington, D.C. (In Press)

    Google Scholar 

  3. Breinig MK, Kingsley LA, Armstrong JA, Freeman DJ, Ho M. Epidemiology of genital herpes in Pittsburgh: serologic, sexual, and racial correlates of apparent and inapparent herpes simplex infection. J Infect Dis 1990; 162: 299–305.

    Article  PubMed  CAS  Google Scholar 

  4. Johnson RE, Nahmias AJ, Magder LS, Lee FK, Brooks CA, Snowden CB. A seroepidemiologic survey of the prevalence of herpes simplex virus type 2 infection in the United States. N Engl J Med 1990; 321: 712.

    Google Scholar 

  5. Corey L. The current trend in genital herpes. Progress in prevention. Sex Trans Dis 1994; 21 (Suppl 2): S38 - S44.

    CAS  Google Scholar 

  6. Johnson R, Lee F, Hadgu A, McQuillan G, Aral S, Keesling S. Nahmias A. US genital herpes trends during the first decade of AIDS - prevalences increased in young whites and elevated in blacks. Abstract. Tenth International Society for STD Research, Helsinki, Finland, August 29-Sept. 1, 1993.

    Google Scholar 

  7. Wald A, Zeh J, Selke S. Ashley RL, Corey L. Subclinical genital herpes has similar virologie characteristics as symptomatic genital herpes. N Engl J Med 1995; 333: 770–775.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

Corey, L., Wald, A., Davis, L.G. (1996). Subclinical Shedding of HSV: Its Potential for Reduction by Antiviral Therapy. In: Mills, J., Volberding, P.A., Corey, L. (eds) Antiviral Chemotherapy 4. Advances in Experimental Medicine and Biology, vol 394. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9209-6_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4757-9209-6_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9211-9

  • Online ISBN: 978-1-4757-9209-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics