Abstract
Australia is entering a joint clinical trial with Japan for thermal Neutron Capture Therapy of selected patients with superficial local recurrent, local advanced and isolated metastatic malignant melanoma. The para-boronophenylalanine (BPA) compound will be used with a neutron fluence of about 1013 neutrons per cm2, to be delivered in a single dose. While in the initial trials of NCT, the single dose is a practical procedure, there may be advantages in dose fractionation, and these are considered in this paper.
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© 1989 Plenum Press, New York
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Allen, B.J., Brown, J.K. (1989). Dose Fractionation in Neutron Capture Therapy for Malignant Melanoma. In: Fairchild, R.G., Bond, V.P., Woodhead, A.D., Vivirito, K. (eds) Clinical Aspects of Neutron Capture Therapy. Basic Life Sciences, vol 50. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5622-6_8
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DOI: https://doi.org/10.1007/978-1-4684-5622-6_8
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