Abstract
Much of the biological research conducted over the last 30 years has been directed toward the ultimate goal of understanding the “body human” in molecular terms. While a direct assault on the molecular biology of man was clearly not feasible prior to the age of recombinant DNA, earlier studies of simpler organisms provided a wealth of information on basic molecular principles that operated in human beings as well. Nevertheless, less complex organisms such as bacteria, yeast, or even Drosophila are not as useful to an understanding of human embryology, immunology, neurobiology, or cancer biology. While it is now possible to perform molecular studies directly on human-derived cell lines and tissues, the human body is still not amenable to analysis with the full range of genetic tools available to the contemporary biologist.
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Silver, L.M., Garrels, J.I., Lehrach, H. (1984). Molecular Studies of Mouse Chromosome 17 and the T Complex. In: Setlow, J.K., Hollaender, A. (eds) Genetic Engineering. Genetic Engineering, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4793-4_8
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DOI: https://doi.org/10.1007/978-1-4684-4793-4_8
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