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Highly Purified Cytochrome P-450 from Liver Microsomal Membranes: Recent Studies on the Mechanism of Catalysis

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Iron and Copper Proteins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 74))

Abstract

The purpose of this paper is to summarize our knowledge of the properties of purified liver microsomal cytochrome P-450, including evidence for multiple forms, and to present data from recent experiments bearing on the mechanism of action of this cytochrome. For the sake of brevity we will confine our discussion to studies in this laboratory on cytochrome P-450 solubilized and purified from rabbit liver microsomes.

Postdoctoral Fellow, United States Public Health Service.

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Author information

Authors and Affiliations

  1. Department of Biological Chemistry, Medical School, The University of Michigan, Ann Arbor, Michigan, USA

    M. J. Coon, D. P. Ballou, F. P. Guengerich, G. D. Nordblom & R. E. White

Authors
  1. M. J. Coon
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  2. D. P. Ballou
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  3. F. P. Guengerich
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  4. G. D. Nordblom
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  5. R. E. White
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Editor information

Editors and Affiliations

  1. University of Hawaii School of Medicine, Honolulu, Hawaii, USA

    Kerry T. Yasunodu  & Howard F. Mower  & 

  2. Kyoto University Faculty of Medicine, Kyoto, Japan

    Osamu Hayaishi

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© 1976 Plenum Press, New York

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Coon, M.J., Ballou, D.P., Guengerich, F.P., Nordblom, G.D., White, R.E. (1976). Highly Purified Cytochrome P-450 from Liver Microsomal Membranes: Recent Studies on the Mechanism of Catalysis. In: Yasunodu, K.T., Mower, H.F., Hayaishi, O. (eds) Iron and Copper Proteins. Advances in Experimental Medicine and Biology, vol 74. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3270-1_20

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  • DOI: https://doi.org/10.1007/978-1-4684-3270-1_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3272-5

  • Online ISBN: 978-1-4684-3270-1

  • eBook Packages: Springer Book Archive

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