Abstract
This short review summarizes the recent work that we have performed on the biochemical and structural properties of nucleoside diphosphate (NDP) kinase.
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References
Biggs, J., E. Hersperger, P. S. Steeg, L. A. Liotta and A. Shearn, 1990, A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase. Cell. 63: 933–940.
Cherfils, J., S. Moréra, I. Lascu, M. Véron and J. Janin, 1994, X-Ray structure of Nucleoside Diphosphate Kinase complexed with dTDP and Mg2+ at 2Å resolution. Biochemistry, in press
Chiadmi, M., S. Moréra, I. Lascu, C. Dumas, G. LeBras, M. Véron and J. Janin, 1993, The Awd Nucleoside Diphosphate Kinase, from Drosophila. Structure. 1: 283–293.
Dumas, C., I. Lascu, S. Morena, P. Glaser, R. Fourme, V. Wallet, M. Lacombe and M. J. Véron J., 1992, X-ray structure of Nucléoside diphiophate kinase. EMBO J. 11: 3203–3208.
Gilles, A. M., E. Presecan, A. Vonica and I. Lascu, 1991, Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polipeptide chains responsible for heterogeneity of the hexameric enzyme. J. Biol. Chem. 266: 8784–8789.
Hailat, N., D. R. Keim, R. F. Melhem, X. Zhu, C. Eckersckorn, G. M. Brodeur, C. P. Reynols, R. C. Seeger, F. Lottspeich, J. R. Strahler and S. M. Hanash, 1991, High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification. J. Clin. Invest. 88: 341–345.
Hildebrandt, M., M. Lacombe, S. Passeron and M. Veron, 1994, Human NDP-Kinase B binds specifically to single-stranded poly-pyrimidine DNA sequences, submitted.
Keim, D., N. Hailat, R. Melhem, X. X. Zhu, I. Lascu, M. Veron, J. Strahler and S. M. Hanash, 1992, Proliferation related expression of P19/NM23 Nucleoside Diphosphate Kinase. J. Clinic. Invest. 89: 919–924.
Lacombe, M. L., V. Wallet, H. Troll and M. Veron, 1990, Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum. J Biol Chem. 265: 10012–8.
Lacombe, M., X. Sastre-Gareau, I. Lascu, V. Wallet, J. Thiery and M. Veron, 1991, Overexpression of Nucleoside Diophosphate Kinase (Nm23) in Human Solid Tumors. Eur. J. Canc. 27: 1302–1307.
Lascu, I., A. Chaffotte, B. Limbourg-Bouchon and M. and Véron, 1992, A Pro/Ser substitution in nucleoside diphosphate kinase of Drosophila melanogaster (mutation Killer of prune) affects stability but not catalytic efficiency of the enzyme. J. Biol. Chem. 267: 12775–12781.
Lascu, I., D. Deville-Bonne, P. Glazer and M. Véron, 1993, Equilibrium dissociation and unfolding of nucleoside diphosphate kinase from Dictyostelium discoideum. Role of proline 100 in the stability of the hexameric enzyme. J. Biol. Chem. 268: 20268–20275.
Leone, A., U. Flatow, C. Richterking, M. Sandeen, I. M. K. Margoulies, L. A. Liotta and P. S. Steeg, 1991, Reduced Tumor Incidence, Metastatic Potential, and Cytokine Responsiveness off Nm23 Transfected Melanoma Cells. Cell. 65: 25–35.
Munoz-Dorado, J., M. Inouye and S. Inouye, 1990, Nucleoside diphosphatase kinase from Myxococcus xanthus. I. Cloning and sequencing of the gene. J. Biol. Chem. 265: 2702–2706.
Postel, E. H., S. J. Berberich, S. J. Flint and C. A. Ferrone, 1993, Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis. Science. 261: 478–480.
Presecan, E., A. Vonica and I. Lascu, 1989, Nucleoside diphosphate kinase from human erythrocytes. Purification, molecular mass and subunit structure. FEBS lett. 250: 629–632.
Rosengard, A. M., H. C. Krutzsch, A. Shearn, J. R. Biggs, E. Barker, I. M. K. Margulies, C. R. King, L. A. Liotta and P. S. Steeg, 1989, Reduced Nm23/Awd protein in tumor metastasis and aberrant Drosophila development. Nature. 342: 177–180.
Sawan, A., I. Lascu, M. Veron, J. J. Anderson, C. Wright, C. H. W. Horne and B. Angus, 1994, NDP-K/nm23 Expression in Human Brest Cancer in Relation to relapse, Survival, and other Prognostic Factors: an Imuunohistochemical Study. J. Pathology. 172: 27–34.
Stahl, J. A., A. Lerone, A. M. Rosengard, L. Porter, C. R. King and P. S. Steeg, 1991, Identification of a second human nm23 gene, nm23-H2. Cancer Res. 51
Steeg, P. S., G. Bevilacqua, L. Kopper, U. P. Thorgeirsson, J. E. Talmadge, L. A. Liotta and M. E. Sobel, 1988, Evidence for a novel gene associated with low tumor metastasic potential., J. Natn. Cancer Inst. 80: 200–204.
Wallet, V., R. Mutzel, H. Troll, O. Barzu, B. Wurster, M. Veron and M. L. Lacombe, 1990, Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development. J Natl Cancer Inst. 82: 1199–202.
Williams, R. L., D. A. Oren, J. Munoz-Dorado, S. Inouye, M. Inouye and E. Arnold, 1993, Crystal structure of Myxococcus xanthus nucleoside diphosphate kinase and its interaction with nucleotide substrate at 2.0Å resolution. J. Mol. Biol 234: 1230–1247.
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Véron, M. et al. (1995). Nucleoside Diphosphate Kinase: an Old Enzyme with New Functions?. In: Sahota, A., Taylor, M.W. (eds) Purine and Pyrimidine Metabolism in Man VIII. Advances in Experimental Medicine and Biology, vol 370. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2584-4_126
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DOI: https://doi.org/10.1007/978-1-4615-2584-4_126
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