Abstract
Episodic or intermittent hypoxia occurs in many pathophysiological situations, including sleep apneas and recurrent apneas in premature infants. In addition, intermittent hypoxia is not all uncommon in humans who have lung diseases such as chronic obstructive pulmonary disease (COPD), asthma or pulmonary fibrosis. Thus mammals experience episodic hypoxia, often in life, even perhaps more so than sustained hypoxia that occurs in situations like high altitude.
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References
E.C. Fletcher, R.D. DeBehnke, M.S. Lovoi, and A.B. Gorin, Undiagnosed sleep apnea in patients with essential hypertension. Ann. Intern. Med. 103:190–195, 1985.
E.C. Fletcher, G. Bao, and C.C. Miller, III, Effects of recurrent episodic hypocapnic, eucapnic, and hypercapnic hypoxia on systemic blood pressure. J. Appl. Physiol. 78:1516–1521, 1995.
L. Ling, E.B. Olson, and G.S. Mitchell, Chronic intermittent hypoxia enhances the hypoxic ventilatory control system. FASEB J. 12: A781, 1998.
J. Przybyski, A. Trzebski, T. Czyzewski, and J. Jodkowski, Responses to hyperoxia, hypoxia, hypercapnia and almitrine in spontaneously hypertensive rats. Bull Eur. Physiopath. Respir. 4: 145–154, 1980.
E.C. Fletcher, J. Miller, J.W. Schaaf, and J.G. Fletcher, Urinary cathecholamines before and after tracheostomy in patients with obstructive sleep apnea and hypertention. Sleep. 10: 35–44, 1987.
N.R. Prabhakar, Oxygen sensing by the carotid body chemoreceptors. J.Appl.Physiol.. 88: 2287–2295, 2000.
F.L. Powell, W.K. Milsom, and G.S. Mitchell, Time domine of the hypoxic ventilatory response. Respir. Physiol. 112: 123–134, 1998.
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Peng, Y., Kline, D.D., Dick, T.E., Prabhakar, N.R. (2001). Chronic Intermittent Hypdxia Enhances Carotid Body Chemoreceptor Response to Low Oxygen. In: Poon, CS., Kazemi, H. (eds) Frontiers in Modeling and Control of Breathing. Advances in Experimental Medicine and Biology, vol 499. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1375-9_5
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DOI: https://doi.org/10.1007/978-1-4615-1375-9_5
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