Abstract
Numerous in vitro cell culture, animal, and tissue homogenate studies have implicated free radical damage in the pathogenesis of Alzheimer’s disease (AD) 1,2. A variety of methods have been employed to assess the free radical damage; however, most of these methods suffer from either non-quantitative results, a lack of information about cellular localization, or both3- 10.
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Reich, E.E., Markesbery, W.R., Roberts, L.J., Swift, L.L., Morrow, J.D., Montine, T.J. (2001). Quantification of F-Ring and D-/E-Ring Isoprostanes and Neuroprostanes in Alzheimer’s Disease. In: Dansette, P.M., et al. Biological Reactive Intermediates VI. Advances in Experimental Medicine and Biology, vol 500. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0667-6_39
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DOI: https://doi.org/10.1007/978-1-4615-0667-6_39
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