Abstract
Precise localisation of cortical activation in the early development of the infant brain remains unclear. It is challenging to co-register haemodynamic responses during functional activation in infants with the underlying anatomy of the brain. We used a multispectral imaging algorithm to reconstruct 3D optical topographic images of haemodynamic responses in an infant during voice processing. In this chapter, we present a method for co-registering 3D optical topography images reconstructed from functional activation data in infants onto anatomical brain images obtained from MRI structurals of the individual infants.
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Acknowledgments
This work was supported by a grant from the Simons Foundation (SFARI 201287 M.J) and the National Institutes of Health, NICHD, R37 HD19842.
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Papademetriou, M.D. et al. (2013). Cortical Mapping of 3D Optical Topography in Infants. In: Van Huffel, S., Naulaers, G., Caicedo, A., Bruley, D.F., Harrison, D.K. (eds) Oxygen Transport to Tissue XXXV. Advances in Experimental Medicine and Biology, vol 789. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7411-1_61
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DOI: https://doi.org/10.1007/978-1-4614-7411-1_61
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