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Benzoylalanine Analogues as Inhibitors of Rat Brain Kynureninase and Kynurenine 3-Hydroxylase

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Recent Advances in Tryptophan Research

Abstract

Alterations in glutamatergic neurotransmission mediated by excitatory amino acid (EAA) receptors are involved in the pathogenesis of several neurological disorders caused by either chronic or acute events (Meldrum, 1990). Accordingly, new neuroprotective strategies aimed at reducing glutamatergic receptor overstimulation have been proposed.

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© 1996 Plenum Press, New York

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Giordani, A. et al. (1996). Benzoylalanine Analogues as Inhibitors of Rat Brain Kynureninase and Kynurenine 3-Hydroxylase. In: Filippini, G.A., Costa, C.V.L., Bertazzo, A. (eds) Recent Advances in Tryptophan Research. Advances in Experimental Medicine and Biology, vol 398. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0381-7_77

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  • DOI: https://doi.org/10.1007/978-1-4613-0381-7_77

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8026-9

  • Online ISBN: 978-1-4613-0381-7

  • eBook Packages: Springer Book Archive

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