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Advances in Male Mediated Developmental Toxicity pp 253–268Cite as

Integrating New Tests of Sperm Genetic Integrity into Semen Analysis: Breakout Group Discussion

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 518))

Abstract

The First International Conference on Male-Mediated Developmental Toxicity, held in September 1992, reported that the spermatozoon can bring genetic damage into the oocyte at fertilization and thereby contribute to subsequent abnormal pregnancy outcomes (Olshan and Mattison, 1994). At that time, laboratory tests for genetic defects in sperm were at an early stage of development and were relatively untested in the clinic and the field. A breakout group at that meeting discussed the need for improved sperm biomarkers of adverse reproductive effects and concluded that sensitive, reliable, and practical methods

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Authors and Affiliations

  1. U.S. EPA, ORD, NHEERL, Reproductive Toxicology Division, Research Triangle Park, NC 27711, USA

    Sally D. Perreault & Rebecca A. Morris

  2. School of Biological & Chemical Sciences, University of Newcastle, Newcastle, NSW, Australia, 2308

    R. John Aitken

  3. Department of Obstetrics and Gynaecology, Royal Women’s Hospital University of Melbourne, Australia

    H. W. Gordon Baker

  4. Olson Biochemistry Laboratories, ASC 136, South Dakota State University, Brookings, 57007, SD, USA

    Donald P. Evenson

  5. Department of Obstetrics and Gynaecology, Yale University School of Medicine, New Haven, CT 06520, USA

    Gabor Huszar & Denny Sakkas

  6. Centre for Reproductive Biology, MRC Human Reproductive Sciences Unit, 37 Chalmers Street, Edinburgh, Scotland, UK, EH3 9ET

    D. Stewart Irvine

  7. Biological Sciences, Stopford Building, University of Manchester, Oxford Road, Manchester, Ml3 9PT, UK

    Ian D. Morris

  8. UCLA Center for Occupational and Environmental Health, 10822 LeConte Ave., Los Angeles, CA 90095, USA

    Wendie A. Robbins

  9. Section of Toxicology & Biomedical Sciences, ENEA CR Casaccia, Via Anguillarese 301, Rome, Italy, 00060

    Marcello Spano

  10. Biology and Biotechnology Research, Lawrence Livermore National Laboratory, 7000 East Avenue, L-448, Livermore, CA 94550, USA

    Andrew J. Wyrobek

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  1. Sally D. Perreault
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  2. R. John Aitken
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  3. H. W. Gordon Baker
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  4. Donald P. Evenson
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  5. Gabor Huszar
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  7. Ian D. Morris
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  8. Rebecca A. Morris
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  9. Wendie A. Robbins
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  10. Denny Sakkas
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  11. Marcello Spano
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  12. Andrew J. Wyrobek
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Editors and Affiliations

  1. McGill University, Montreal, Quebec, Canada

    Bernard Robaire  & Barbara F. Hales  & 

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Perreault, S.D. et al. (2003). Integrating New Tests of Sperm Genetic Integrity into Semen Analysis: Breakout Group Discussion. In: Robaire, B., Hales, B.F. (eds) Advances in Male Mediated Developmental Toxicity. Advances in Experimental Medicine and Biology, vol 518. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9190-4_23

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  • DOI: https://doi.org/10.1007/978-1-4419-9190-4_23

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