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Feedback Control of Microflows

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Feedback Control of MEMS to Atoms

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Abstract

This chapter gives an overview of methods we have developed and experimental results we have achieved for precision feedback control of flows and objects inside microfluidic systems. Essentially, we are doing flow control, but flow control on the microscale, and further even to nanoscale accuracy, to precisely and robustly manipulate liquid packets, particles (e.g., cells and quantum dots), and micro- and nanoobjects (e.g., nanowires). Target applications include methods to miniaturize the operations of a biological laboratory (lab-on-a-chip), e.g., presenting pathogens to on-chip sensing cells or extracting cells from messy biosamples such as saliva, urine, or blood; as well as nonbiological applications such as deterministically placing quantum dots on photonic crystals to make multidot quantum information systems.

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Acknowledgments

This research was supported by funding from the National Science Foundation (CAREER award), DARPA, and AFOSR. There is also current funding support from the National Institutes of Health to begin to transition these results from laboratory to medical research and clinical use. Success in this area relies on many collaborators that we would like to acknowledge and thank: Pamela Abshire, Andrew Berglund, Michael Emmert-Buck, Robin Garrell, “CJ” Kim, Alex Liddle, Andreas Lubbe, Ricardo Nochetto, Juan Santiago, Elisabeth Smela, and Ian White.

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Authors and Affiliations

  1. Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, Bethesda, MD, USA

    Mike Armani

  2. Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA

    Mike Armani, Zach Cummins & Roland Probst

  3. Micromanufacturing Laboratory, University of California, Los Angeles, CA, USA

    Jian Gong

  4. Aerospace Engineering, University of Maryland, College Park, MD, USA

    Pramod Mathai

  5. Electrical Engineering, University of Maryland, College Park, MD, USA

    Chad Ropp

  6. Electrical Engineering & Institute for Research in Electronics and Applied Physics (IREAP), University of Maryland, College Park, MD, USA

    Edo Waks

  7. Department of Mathematics & Center for Computation and Technology (CCT), Louisiana State University, Baton Rouge, LA, USA

    Shawn Walker

  8. Fischell Department of Bioengineering & Institute for Systems Research, University of Maryland, College Park, MD, USA

    Benjamin Shapiro

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  1. Mike Armani
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Correspondence to Benjamin Shapiro .

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Editors and Affiliations

  1. Technology (NIST), Intelligent Systems Division, National Institute of Standards &, Bureau Drive 100, Gaithersburg, 20899, Maryland, USA

    Jason J. Gorman

  2. Fischell Department of Bioengineering, University of Maryland, 1226 Kim Building 3178, College Park, 20742, Maryland, USA

    Benjamin Shapiro

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Armani, M. et al. (2012). Feedback Control of Microflows. In: Gorman, J., Shapiro, B. (eds) Feedback Control of MEMS to Atoms. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5832-7_9

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