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The Caries Process in Dentine: The Response of Dentine and Pulp

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Dental Caries
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Abstract

Although caries of enamel is clearly a dynamic process, it is not a vital process in the sense that living, cellular reactions occur. Indeed, enamel is almost a unique tissue, because it is devoid of cells and cannot, therefore, respond to injury.

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Further Reading

  • Baume, L. J. (1970). Diagnosis of diseases of the pulp. Oral Surgery, 29, 102–16

    Article  Google Scholar 

  • Finn, S. B. (1968). Biology of the Dental Pulp Organ, University of Alabama Press

    Google Scholar 

  • Fish, E. W. (1948). Surgical Pathology of the Mouth, Pitman, London

    Google Scholar 

  • Massler, M (1967). Pulpal reactions to dental caries. International Dental Journal, 17, 441–60

    Google Scholar 

  • Seltzer, S. and Bender, I. B. (1975). The Dental Pulp, Lippincott, Philadelphia and Toronto

    Google Scholar 

  • Symonds, N. B. B. (Ed) (1968). Dentine and Pulp: Their Structure and Reactions, University of Dundee

    Google Scholar 

References

  1. Johnson, N. W., Taylor, B. R. and Berman, D. S. (1969). The response of deciduous dentine to caries studied by correlated light and electron microscopy. Caries Research, 3, 348–68

    Article  Google Scholar 

  2. Weber, D. F. (1974). Human dentine sclerosis: a microradiographic survey. Archives of Oral Biology, 19, 163–9

    Article  Google Scholar 

  3. Levine, R. S. (1972). The distribution of hydroxyproline in the dentine of carious teeth. Archives of Oral Biology, 17, 127–35

    Article  Google Scholar 

  4. Bradford, E. W. (1960). The dentine, abarrier to caries. British Dental Journal, 109, 387–98

    Google Scholar 

  5. Frank, R. M. (1970). Etude autoradiographique de la dentinogènese en microscopies électronique à l’aide de la proline tritiée chez le chat. Archives of Oral Biology, 15, 583–96

    Article  Google Scholar 

  6. Nalbandian, J., Gonzales, F. and Sognnaes, R. F. (1960). Sclerotic age changes in root dentine of human teeth as observed by optical, electron and X-ray microscopy. Journal of Dental Research, 39, 598–607

    Article  Google Scholar 

  7. Miles, A. E. W. (1976). Age changes in dental tissues, in Scientific Basis of Dentistry (Eds Cohen, B and Kramer I. R. H. ), Livingstone, Edinburgh and London, pp. 363–75

    Google Scholar 

  8. Frank, R. M., Wolff, F. and Gutmann, B. (1964). Microscopie électronique de la carie au mileu de la dentine humain. Archives of Oral Biology, 9, 163–79

    Article  Google Scholar 

  9. Levine, R. S. (1974). The microradiographic features of dentine caries. British Dental Journal, 137, 301–6

    Article  Google Scholar 

  10. Barber, D. and Massler, M. (1964). Permeability of active and arrested carious lesions to dyes and radioactive isotopes. Journal of Dentistry for Children, 31, 26–33

    Google Scholar 

  11. Fish, E. W. (1948). Surgical Pathology of the Mouth, Pitman, London

    Google Scholar 

  12. Corbett, M. E. (1963). Incidence of secondary dentine present in carious teeth. British Dental Journal, 114, 142–6

    Google Scholar 

  13. Darling, A. I. (1959). The pathology and prevention of caries. British Dental Journal, 107, 287–302

    Google Scholar 

  14. Dwyer, D. M., Berman, D. S. and Silverstone, L. M. (1973). A study of approximal carious lesions in primary molars. Journal of the International Association of Dentistry for Children, 4, 41–6

    Google Scholar 

  15. Backer Dirks, O. (1966). Posteruptive changes in dental enamel. Journal of Dental Research, 45, 503–11

    Article  Google Scholar 

  16. Berman, D. S. and Slack, G. L. (1973). Caries progression and activity in approximal tooth surfaces: a longitudinal study. British Dental Journal, 134, 51–7

    Article  Google Scholar 

  17. Taylor, B. R., Berman, D. S. and Johnson, N. W. (1971). The response of pulp and dentine to dental caries in primary molars. Journal of the International Association of Dentistry for Children, 2, 3–9

    Google Scholar 

  18. MacGregor, A. B., Marsland E. A. and Batty, I. (1956). Experimental studies of dental caries I: The relation of bacterial invasion to the softening of the dentine. British Dental Journal, 101, 230–5

    Google Scholar 

  19. Fusayama, T. (1972). Structure and removal of carious dentine. International Dental Journal, 22, 401–11

    Google Scholar 

  20. Shovelton, D. S. (1968) A study of deep carious dentine. International Dental Journal, 18, 392–405

    Google Scholar 

  21. Shovelton, D. S. (1972) The maintenance of pulp vitality. British Dental Journal, 133, 95–107

    Article  Google Scholar 

  22. Sarnat, H. and Massler, M. (1965) Microstructure of active and arrested dentinal caries. Journal of Dental Research, 44, 1389–1401

    Article  Google Scholar 

  23. Symonds, N. B. B. (1970). Electron microscopic study of the tubules in human carious dentine. Archives of Oral Biology, 15, 239–51

    Article  Google Scholar 

  24. Massler, M. (1967). Pulpal reactions to dental caries. International Dental Journal, 17, 441–60

    Google Scholar 

  25. Paterson, R. C. (1974). Management of the deep cavity. British Dental Journal, 137, 250–2

    Article  Google Scholar 

  26. Whitehead, I., MacGregor, A. B. and Marsland, E. A. (1960). Experimental studies of dental caries II: The relation of bacterial invasion to softening of the dentine in permanent and deciduous teeth. British Dental Journal, 108, 261–5

    Google Scholar 

  27. Yoon, S. H., Brudevold, F., Gardner, D. and Smith, F. (1960). Distribution of fluoride in teeth from areas with different levels of fluoride in the water supply. Journal of Dental Research, 39, 845–56

    Article  Google Scholar 

  28. Reeves, R. and Stanley, H. R. (1966). The relationship of bacterial penetration and pulpal pathosis in carious teeth. Oral Surgery, 22, 59–65

    Article  Google Scholar 

  29. Bergenholtz, G. (1977). Effect of bacterial products on inflammatory reactions in the dental pulp. Scandinavian Journal of Dental Research, 85, 122–9

    Google Scholar 

  30. Fisher, F. J. (1966). The viability of microorganisms in carious dentine beneath amalgam restorations. British Dental Journal, 121, 413–16

    Google Scholar 

  31. Fisher, F. J. (1969). The viability of microorganisms in carious dentine beneath amalgam restorations. British Dental Journal, 126, 355–6

    Google Scholar 

  32. MacGregor, A. B. (1962). The extent and distribution of acid in carious dentine. Proceedings of the Royal Society of Medicine, 55, 1063–6

    Google Scholar 

  33. King, J. B., Crawford, J. J. and Lindahl, R. L. (1965). Indirect pulp capping: a bacteriologic study of deep carious dentine in human teeth. Oral Surgery, 20, 633–71

    Google Scholar 

  34. Mjör, I. A., Finn, S. B. and Quigley, M. B. (1961). The effect of calcium hydroxide and amalgam on non carious, vital dentine. Archives of Oral Biology, 3, 283–91

    Google Scholar 

  35. Fisher, F. J. (1972). The effect of a calcium hydroxide/water paste on micro-organisms in carious dentine. British Dental Journal, 133, 19–21

    Article  Google Scholar 

  36. Mjör, I. A. (1967). Histologic studies of human coronal dentine following the insertion of various materials in experimentally prepared cavities. Archives of Oral Biology, 12, 441–52

    Article  Google Scholar 

  37. Eidelman, E., Finn, S. B. and Koulorides, T. (1965). Remineralization of carious dentine treated with calcium hydroxide. Journal of Dentistry for Children, 32, 218–25

    Google Scholar 

  38. McKay, G. S. (1976). The histology and microbiology of acute occlusal dentine lesions in human permanent molar teeth. Archives of Oral Biology, 21, 51–8

    Article  Google Scholar 

  39. Loesche, W. J. and Syed, S. A. (1973). The predominant cultivable flora of carious plaque and carious dentine. Caries Research 7, 201–16

    Article  Google Scholar 

  40. Edwardsson, S. (1974). Bacteriological studies on deep areas of carious dentine. Odontologisk Revy, 25, suppl. 32

    Google Scholar 

  41. Crawford, J. J. and Shankle, R. J. (1961). Application of new methods to study the importance of root canal and oral microbiota in endodontics. Oral Surgery, 14, 1109–23

    Article  Google Scholar 

  42. Winkler, K. C. and Van Amerongen, J. (1959). Bacteriologic results from 4000 root canal cultures. Oral Surgery, 12, 857–75

    Article  Google Scholar 

  43. Larmas, M. (1972). Histochemical demonstration of various dehydrogeneses in human carious dentine. Archives of Oral Biology, 17, 1143–53

    Article  Google Scholar 

  44. Johnansen, E. and Parks, H. F. (1961). Electron microscopic observations on soft carious human dentine. Journal of Dental Research, 40, 235–8

    Article  Google Scholar 

  45. Lester, K. S. and Boyde, A. (1968). Some preliminary observations on caries (`re-mineralisation’) crystals in enamel and dentine by surface electron microscopy. Virchows Archives of Pathology and Anatomy, 344, 196–212

    Article  Google Scholar 

  46. Vahl, J., Höhling, H. J. and Frank, R. M. (1964). Elektronen strahlbeugung am rhomboedrisch aussebenden Mineralbildungen in kariösem dentin. Archives of Oral Biology, 9, 315–20

    Article  Google Scholar 

  47. Larmas, M. (1972). A chromatographic and histochemical study of non-specific esterases in human carious dentine. Archives of Oral Biology, 17, 1121–32

    Article  Google Scholar 

  48. Larmas, M. (1972). Alanine and aspartate aminotransferases in sound and carious human dentine. Archives of Oral Biology, 17, 1133–41

    Article  Google Scholar 

  49. Karjalainen, S. and Larmas, M. (1975). Quantitative study of the arylaminopeptidase activity in normal and altered states of human dentine. Caries Research, 9, 340–50

    Article  Google Scholar 

  50. Willner, H. (1926). Untersuchungen über des Vorkommen von Fett in der ZahnPulpa. Zeitschrift fur stomatologie, 24, 1084–92

    Google Scholar 

  51. Allred, H. (1969). The staining of the lipids in carious human dentine Archives of Oral Biology, 14, 271–6

    Article  Google Scholar 

  52. Mäkinen, K. K. (1970). Characteristics of the hydrolysis of 4-phenylazobenzyloxy-carbonyl-1-prolyl-1-leucylglycyl-1-prolyl-D-arginine (a collagenase substrate) by enzyme preparations derived from carious dentine. Acta Odontologica Scandinavica, 28, 485–97

    Article  Google Scholar 

  53. Bergman, G. and Anneroth, G. (1972). A semiquantitative microradiographic study of the distribution of organic mass in human carious dentine. Archives of Oral Biology, 17, 201–9

    Article  Google Scholar 

  54. Miller, W. A. and Massler, M. (1962). Permeability and staining of active and arrested lesions in dentine. British Dental Journal, 112, 187–97

    Google Scholar 

  55. Kuwabara, R. K. and Massler, M. (1966). Pulpal reactions to active and arrested carious lesions. Journal of Dentistry for Children, 33, 190–204

    Google Scholar 

  56. Takuma, S., Ogiwara, H. and Suzuki, H. (1975). Electron probe and electron microscope studies of carious dentinal lesions with a remineralised surface layer. Caries Research, 9, 278–85

    Article  Google Scholar 

  57. Levine, R. S. (1973). The differential inorganic composition of dentine within active and arrested carious lesions. Caries Research, 7, 245–60

    Article  Google Scholar 

  58. Levine, R. S. (1972). Distribution of fluoride in active and arrested carious lesions in dentine. Journal of Dental Research, 51, 1025–9

    Google Scholar 

  59. Rowles, S. L. and Levine, R. S. (1973). The inorganic composition of arrested carious dentine. Caries Research, 7, 360–7

    Article  Google Scholar 

  60. Levine, R. S. (1972). Remineralisation of human carious dentine in vitro. Archives of Oral Biology, 17, 1005–8

    Article  Google Scholar 

  61. Levine, R. S. and Rowles, S. K. (1973). Further studies on the remineralisation of human carious dentine in vitro. Archives of Oral Biology, 18, 1351–6

    Article  Google Scholar 

  62. Causton, B. E., Samarawickrama, D. Y. D. and Johnson, N. W. (1976). Effects of calcifying fluid on bonding of cements and composites to dentine in vitro. British Dental Journal, 140, 339–42

    Article  Google Scholar 

  63. Mehta, F. S. and Schroff, B. C. (1965). Aspects of dental diseases in Indian Aborigines. Indian Dental Journal, 15, 182

    Google Scholar 

  64. Jordan, H. U. and Sumney, D. I. (1973). Root surface caries: review of literature and significance of the problem. Journal of Periodontal Research, 44, 158–63

    Article  Google Scholar 

  65. Hazen, S. P., Chilton, N. W. and Mumma, R. D. (1973). The problem of root caries with literature review and clinical description. Journal of The American Dental Association, 86, 137–44

    Article  Google Scholar 

  66. Gustafsson, B. E., Quensel, C. D., Lanke, L. S., Lundqvist, C., Grahnen, H., Bonow, B. E. and Krasse, B. (1954). The Vipeholm dental caries study: the effect of different levels of carbohydrate intake on caries activity in 436 individuals observed for 5 years. Acta Odontologica Scandinavica, 11, 232–364

    Article  Google Scholar 

  67. Westbrook, J. C., Miller, A. D., Chilton, N. W., Williams, F. L. and Mumma, R. D. (1974). Root surface caries: a clinical, histopathologic and microradiographic investigation. Caries Research, 8, 249–55

    Article  Google Scholar 

  68. Keyes, P. H. (1970). Reappraisal of various types of dental caries, in Proceedings 27th Annual Meeting of American Institute of Oral Biology, Palm Springs, pp. 101–11

    Google Scholar 

  69. Krasse, B. (1977). Microbiology of the gingival plaque, in The Borderland between Caries and Periodontal Disease (Ed. Lehner T. ), Academic Press, London

    Google Scholar 

  70. Sumney, D. L. and Jordan, H. L. (1974). Characterisation of bacteria isolated from human root surface carious lesions. Journal of Dental Research, 53, 343–51

    Google Scholar 

  71. Syed, S. A., Loesche, W. J., Pape, H. L. Jr. and Grenier, E. (1975). Predominant cultivable flora isolated from human root-surface caries plaque. Infection and Immunity, 11, 727–31

    Google Scholar 

  72. Williams, N. B. (1955). In Kronfelds Histopathology of the Teeth and their Surrounding Structures, 4th ed. (Ed. Boyle, P. E. ), Lee and Febiger, Philadelphia chap. 5, pp. 258–72

    Google Scholar 

  73. Kostlan, J. (1963). L’image histologique de la carie du cement dentaire. Bulletin du Groupment International pour la Recherche Scientifique en Stomatologie, 6, 339–53

    Google Scholar 

  74. Furseth R. and Johansen, E. (1970). A microradiographic comparison of sound and carious human dental cementum. Archives of Oral Biology, 13, 197–1206

    Google Scholar 

  75. Furseth, R. (1971). Further observations on the fine structure of orally exposed and carious human dental cementum. Archives of Oral Biology, 16, 71–85

    Article  Google Scholar 

  76. Boling, L. R. and Robinson J. B. G. (1938). Vascular changes in the exposed pulp. Journal of Dental Research, 17, 310 (abstract)

    Google Scholar 

  77. Stenvik, A., Iversen, J. and Mjor, I. A. (1972). Tissue pressures and histology of normal and inflamed tooth pulps in macaque monkeys. Archives of Oral Biology, 17, 1501–11

    Article  Google Scholar 

  78. Van Hassel, J. H. (1971). Physiology of the human dental pulp. Oral Surgery, 32, 126–34

    Article  Google Scholar 

  79. Ahlberg, K. F. (1978). Functional studies on experimentally induced inflammatory reactions in the feline tooth pulp. Thesis, Univ. of Stockholm

    Google Scholar 

  80. Cowley, G. and MacPhee, T. (1975). Essentials of Periodontology and Periodontics 2nd edn Livingstone, Edinburgh

    Google Scholar 

  81. Schluger, S., Yuodelis, R. A. and Page, R. C. (1977). Periodontal Disease. Lee and Febiger, Philadelphia

    Google Scholar 

  82. Brandtzaeg, P. (1975). In Oral Mucosa in Health and Disease, (Ed. Dolby, A. E.), Blackwell Scientific Publications, Oxford and Edinburgh

    Google Scholar 

  83. Pulver, W. H., Taubman, M. A. and Smith, D. J. (1977). Immune components in normal and inflamed human dental pulp. Archives of Oral Biology, 22, 103–11

    Article  Google Scholar 

  84. Stephan, R. M. (1937). Correlation of clinical tests with microscopic pathology of the dental pulp. Journal of Dental Research, 16, 267–78

    Article  Google Scholar 

  85. Herbert, W. E. (1945). A correlation of the clinical signs and symptoms and histological conditions of the pulps of 52 teeth. British Dental Journal, 78, 161–74

    Google Scholar 

  86. Langeland, K. (1959). Histological evaluation of pulpal reactions to operative procedures. Oral Surgery, 12, 1235–48, 1357–71

    Google Scholar 

  87. Seltzer, S., Bender, I. B. and Zionitz, M. (1963). The dynamics of pulpal inflammation: correlations between diagnostic data and actual histologic findings in the pulp. Oral Surgery, 16, 846–71; 969–77

    Google Scholar 

  88. Eidelman, E., Touma, B. and Ulmansky, M. (1968). Pulp pathology in deciduous teeth: clinical and histological considerations. Israel Journal of Medical Science, 4, 1244–8

    Google Scholar 

  89. Garfunkel, A. (1973). Dental pulp pathosis: clinico-pathologic correlations based on 109 cases, Oral Surgery, 35, 110–17

    Article  Google Scholar 

  90. Schröder, U. (1977). Agreement between clinical and histologic findings in chronic coronal pulpitis in primary teeth. Scandinavian Journal of Dental Research, 85, 583–7

    Google Scholar 

  91. Koch, G. and Nyborg, H. (1970). Correlation between clinical and histological indications for pulpotomy of deciduous teeth. Journal of the International Association of Dentistry for Children, 1, 3–10

    Google Scholar 

  92. Radden, H. G. (1939). Chronic hypertrophic pulpitis. Thesis, Univ. of Melboume.

    Google Scholar 

  93. Tyldesley, W. R. and Mumford, J. M. (1970). Dental pain and the histological condition of the pulp. Dental Practitioner and Dental Record, 20, 333–6

    Google Scholar 

  94. Mathews, B., Searle, B. N., Adams, D. and Linden, R. (1974). Thresholds of vital and non vital teeth to stimulation with electric pulp testers. British Dental Journal, 137, 352–5

    Article  Google Scholar 

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© 1981 L. M. Silverstone, N. W. Johnson, J. M. Hardie and R. A. D. Williams

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Silverstone, L.M., Johnson, N.W., Hardie, J.M., Williams, R.A.D. (1981). The Caries Process in Dentine: The Response of Dentine and Pulp. In: Dental Caries. Palgrave, London. https://doi.org/10.1007/978-1-349-16547-6_7

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  • DOI: https://doi.org/10.1007/978-1-349-16547-6_7

  • Publisher Name: Palgrave, London

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