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Animal Models of Tauopathy

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Alzheimer’s Disease

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6. Conclusion

Overall, animal models exist that replicate most, if not all of the pathological features of tauopathies. New models such as the inducible tau mouse will be especially useful to order events in pathogenesis, and mice that develop both amyloid plaques and tangles will be valuable tools for testing drugs.

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Authors and Affiliations

  1. Department of Psychiatry Department of Physiology & Neuroscience, New York University School of Medicine, New York

    Karen Duff, Pavan Krishnamurthy & Emmanuel Planel

  2. Mayo Clinic College of Medicine, 4500 San Pablo, Jacksonville, FL, 32224

    Michael Hutton

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  1. Karen Duff
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  2. Pavan Krishnamurthy
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  3. Emmanuel Planel
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  4. Michael Hutton
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Editors and Affiliations

  1. The University of Chicago, IL

    Sangram S. Sisodia

  2. Massachusetts General Hospital and Harvard Medical School, USA

    Rudolph E. Tanzi

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Duff, K., Krishnamurthy, P., Planel, E., Hutton, M. (2007). Animal Models of Tauopathy. In: Sisodia, S.S., Tanzi, R.E. (eds) Alzheimer’s Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-35135-3_13

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