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Effects of Exposure to Welding Fume on Lung Function: Results from the German WELDOX Study

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Environment Exposure to Pollutants

Abstract

The association between exposure to welding fume and chronic obstructive pulmonary disease (COPD) has been insufficiently clarified. In this study we assessed the influence of exposure to welding fume on lung function parameters. We investigated forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC, and expiratory flow rates in 219 welders. We measured current exposure to respirable particles and estimated a worker’s lifetime exposure considering welding techniques, working conditions and protective measures at current and former workplaces. Multiple regression models were applied to estimate the influence of exposure to welding fume, age, and smoking on lung function. We additionally investigated the duration of working as a welder and the predominant welding technique. The findings were that age- and smoking-adjusted lung function parameters showed no decline with increasing duration, current exposure level, and lifetime exposure to welding fume. However, 15 % of the welders had FEV1/FVC below the lower limit of normal, but we could not substantiate the presence of an association with the measures of exposure. Adverse effects of cigarette smoking were confirmed. In conclusion, the study did not support the notion of a possible detrimental effect of exposure to welding fume on lung function in welders.

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References

  • American Thoracic Society (1995) Standardization of spirometry. Am J Respir Crit Care Med 152:1107–1136

    Article  Google Scholar 

  • Antonini JM (2003) Health effects of welding. Crit Rev Toxicol 33:61–103

    Article  CAS  PubMed  Google Scholar 

  • Blanc PD (2012) Occupation and COPD: a brief review. J Asthma 49:2–4

    Article  PubMed  Google Scholar 

  • Chinn DJ, Stevenson IC, Cotes JE (1990) Longitudinal respiratory survey of shipyard workers: effects of trade and atopic status. Br J Ind Med 47:83–90

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chinn DJ, Cotes JE, el Gamal FM, Wollaston JF (1995) Respiratory health of young shipyard welders and other tradesmen studied cross sectionally and longitudinally. J Occup Environ Med 52:33–42

    Article  CAS  Google Scholar 

  • Chinn DJ, Cotes JE, Reed JW (1996) Longitudinal effects of change in body mass on measurements of ventilatory capacity. Thorax 51:699–704

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • de Oca MM, Halbert RJ, Lopez MV, Perez-Padilla R, Talamo C, Moreno D, Muino A, Jardim JR, Valdivia G, Pertuze J, Menezes AM (2012) The chronic bronchitis phenotype in subjects with and without COPD: the PLATINO study. Eur Respir J 40:28–36

    Article  PubMed  Google Scholar 

  • Erkinjuntti-Pekkanen R, Slater T, Cheng S, Fishwick D, Bradshaw L, Kimbell-Dunn M, Dronfield L, Pearce N (1999) Two year follow up of pulmonary function values among welders in New Zealand. J Occup Environ Med 56:328–333

    Article  CAS  Google Scholar 

  • Fishwick D, Bradshaw LM, Slater T, Pearce N (1997) Respiratory symptoms, across-shift lung function changes and lifetime exposures of welders in New Zealand. Scand J Work Environ Health 23:351–358

    Article  CAS  PubMed  Google Scholar 

  • Gabriel S, Koppisch D, Range D (2010) The MGU – a monitoring system for the collection and documentation of valid workplace exposure data. Gefahrstoffe-Reinhaltung der Luft – Air Qual Control 70:43–49

    Google Scholar 

  • Gerin M, Fletcher AC, Gray C, Winkelmann R, Boffetta P, Simonato L (1993) Development and use of a welding process exposure matrix in a historical prospective study of lung cancer risk in European welders. Int J Epidemiol 22(Suppl 2):S22–S28

    Article  PubMed  Google Scholar 

  • GOLD – Global Initiative for Chronic Obstructive Lung Disease (2011) Global strategy for the diagnosis, management and prevention of COPD. Available from http://www.goldcopd.org/guidelines-global-strategy-for-diagnosis-management.html. Accessed 24 Sept 2013

  • Hebisch R, Fricke H-H, Hahn J-U, Lahaniatis M, Maschmeier C-P, Mattenklott M (eds) (2005) Sampling and determining aerosols and their chemical compounds. Wiley-VCH, Weinheim, pp 3–40

    Google Scholar 

  • Hoffmeyer F, Raulf-Heimsoth M, Bruning T (2009) Exhaled breath condensate and airway inflammation. Curr Opin Allergy Clin Immunol 9:16–22

    Article  PubMed  Google Scholar 

  • Kendzia B, Kendzia B, Behrens T, Jöckel KH, Siemiatycki J, Kromhout H, Vermeulen R, Peters S, Van Gelder R, Olsson A, Brüske I, Wichmann HE, Stücker I, Guida F, Tardón A, Merletti F et al (2013) Welding and lung cancer in a pooled analysis of case-control studies. Am J Epidemiol 178:1513–1525

    Article  PubMed Central  PubMed  Google Scholar 

  • Lehnert M, Pesch B, Lotz A, Pelzer J, Kendzia B, Gawrych K, Heinze E, Van GR, Punkenburg E, Weiss T, Mattenklott M, Hahn JU, Mohlmann C, Berges M, Hartwig A, Bruning T (2012) Exposure to inhalable, respirable, and ultrafine particles in welding fume. Ann Occup Hyg 56:557–567

    CAS  PubMed Central  PubMed  Google Scholar 

  • Lehnert M, Weiss T, Pesch B, Lotz A, Zilch-Schöneweis S, Heinze E, Van Gelder R, Hahn JU, Brüning T, The WELDOX Study Group (2013) Reduction in welding fume and metal exposure of stainless steel welders: an example from the WELDOX study. Int Arch Occup Environ Health, Epub ahead of print. doi:10.1007/s00420-013-0884-7

  • Malinovschi A, Backer V, Harving H, Porsbjerg C (2012) The value of exhaled nitric oxide to identify asthma in smoking patients with asthma-like symptoms. Respir Med 106:794–801

    Article  PubMed  Google Scholar 

  • Pesch B, Weiss T, Kendzia B, Henry J, Lehnert M, Lotz A, Heinze E, Kafferlein HU, Van GR, Berges M, Hahn JU, Mattenklott M, Punkenburg E, Hartwig A, Bruning T (2012) Levels and predictors of airborne and internal exposure to manganese and iron among welders. J Expo Sci Environ Epidemiol 22:291–298

    Article  CAS  PubMed  Google Scholar 

  • Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC (1993) Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 16:5–40

    Article  CAS  PubMed  Google Scholar 

  • Quanjer PH, Stanojevic S, Cole TJ, Baur X, Hall GL, Culver BH, Enright PL, Hankinson JL, Ip MS, Zheng J, Stocks J (2012) Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations. Eur Respir J Suppl 40:1324–1343

    Article  Google Scholar 

  • Swanney MP, Ruppel G, Enright PL, Pedersen OF, Crapo RO, Miller MR, Jensen RL, Falaschetti E, Schouten JP, Hankinson JL, Stocks J, Quanjer PH (2008) Using the lower limit of normal for the FEV1/FVC ratio reduces the misclassification of airway obstruction. Thorax 63:1046–1051

    Article  CAS  PubMed  Google Scholar 

  • Szram J, Schofield SJ, Cosgrove MP, Cullinan P (2013) Welding, longitudinal lung function decline and chronic respiratory symptoms: a systematic review of cohort studies. Eur Respir J 42:1186–1193

    Article  PubMed  Google Scholar 

  • Thaon I, Demange V, Herin F, Touranchet A, Paris C (2012) Increased lung function decline in blue-collar workers exposed to welding fumes. Chest 142:192–199

    Article  PubMed  Google Scholar 

  • Weiss T, Pesch B, Lotz A, Gutwinski E, Van GR, Punkenburg E, Kendzia B, Gawrych K, Lehnert M, Heinze E, Hartwig A, Kafferlein HU, Hahn JU, Bruning T (2013) Levels and predictors of airborne and internal exposure to chromium and nickel among welders-results of the WELDOX study. Int J Hyg Environ Health 216:175–183

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

B.P. and T.B. contributed equally to this work.

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The authors declare no conflicts of interest in relation to this article.

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Correspondence to M. Lehnert .

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© 2014 Springer International Publishing Switzerland

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Lehnert, M. et al. (2014). Effects of Exposure to Welding Fume on Lung Function: Results from the German WELDOX Study. In: Pokorski, M. (eds) Environment Exposure to Pollutants. Advances in Experimental Medicine and Biology(), vol 834. Springer, Cham. https://doi.org/10.1007/5584_2014_65

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