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Indoor and Outdoor Pollution as Risk Factor for Allergic Diseases of the Skin and Lungs

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Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 268))

Abstract

Air pollution is worldwide a major public health problem and affects large part of the population. Air pollution does not only harm the respiratory tract system but also the other organs of the body. The damage may result directly from the pollutants toxicity, because the pollutant enters into the organs through a direct route or indirectly through systemic inflammation. There is accumulating evidence suggesting that ambient air pollution not only affects the human lung and the cardiovascular system, but also has negative effects on allergic diseases. In this regard, it has been shown that exposure increases the risk of allergies and eczema in children and adults. However, the mechanism how ambient air pollution affects the skin is not well investigated up to now and needs further research.

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Author information

Authors and Affiliations

  1. IUF – Leibniz Institut für Umweltmedizinische Forschung gGmbH, Düsseldorf, Germany

    Tamara Schikowski

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  1. Tamara Schikowski
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Correspondence to Tamara Schikowski .

Editor information

Editors and Affiliations

  1. Department of Environmental Medicine, University Augsburg, Medical Faculty, Augsburg, Germany

    Claudia Traidl-Hoffmann

  2. Charité - Universitätsmedizin Berlin, Klinik für Dermatologie, Berlin, Berlin, Germany

    Torsten Zuberbier

  3. Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hanover, Germany

    Thomas Werfel

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Schikowski, T. (2021). Indoor and Outdoor Pollution as Risk Factor for Allergic Diseases of the Skin and Lungs. In: Traidl-Hoffmann, C., Zuberbier, T., Werfel, T. (eds) Allergic Diseases – From Basic Mechanisms to Comprehensive Management and Prevention . Handbook of Experimental Pharmacology, vol 268. Springer, Cham. https://doi.org/10.1007/164_2021_503

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