Skip to main content
Log in

Apatite formation on anodized Ti-6Al-4V alloy in simulated body fluid

  • Published:
Metals and Materials International Aims and scope Submit manuscript

Abstract

Titania layers were successfully prepared on the surfaces of Ti-6Al-4V alloy via anodic oxidation in H2SO4 or Na2SO4 solutions at room temperature. The titania layers consisted of pure rutile or a mixture of anatase and rutile structures after the Ti-6Al-4V alloy had been anodized in 1.0 M H2SO4 solution at 150 V or 0.5M Na2SO4 solution at 100 or 130 V. Good apatite-forming ability was demonstrated in simulated body fluid. However, surface layers with mainly titanium metallic phase or a pure anatase structure did not possess the ability to induce apatite formation. Anodic oxidation is an effective method to prepare bioactive Ti-6Al-4V alloy that can be used as an artificial bone substitute under load-bearing applications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. R. Van Noort, J. Mater. Sci. 22, 3801 (1987).

    Article  Google Scholar 

  2. M. Therin, A. Meunier, and P. Christel, J. Mater. Sci.: Mater. Med. 2, 1 (1991).

    Article  Google Scholar 

  3. K. Wang, Mater. Sci. Eng. A 213, 134 (1996).

    Article  Google Scholar 

  4. B. D. Ratner, Titanium in Medicine: Materials Science, Surface Science, Engineering, Biological Responses and Medical Applications (eds., D. M. Brunette, P. Tengvall, M. Textor, and P. Thomsen), p. 1, Springer, MA (2001).

    Google Scholar 

  5. M. P. Thomsen, A. S. Eriksson, R. Olsson, L. M. Bjursten, P. I. Branemark, and L. E. Ericson, Adv. Biomater. 7, 87 (1987).

    Google Scholar 

  6. K. de Groot, R. G. T. Geesink, C. P. A. T. Klein, and P. Serekian, J. Biomed. Mater. Res. 21, 1375 (1987).

    Article  Google Scholar 

  7. M. Shirkhanzadeh, J. Mater. Sci.: Mater. Med. 3, 322 (1992).

    Article  CAS  Google Scholar 

  8. H. Ishizawa and M. Ogino, J. Biomed. Mater. Res. 29, 65 (1995).

    Article  CAS  Google Scholar 

  9. H.-M. Kim, F. Miyaji, T. Kokubo, and T Nakamura, J. Biomed. Mater. Res. 32, 409 (1996).

    Article  CAS  Google Scholar 

  10. X. L. Zhu, K. H. Kim, and Y. Jeong, Biomaterials 22, 2199 (2001).

    Article  CAS  Google Scholar 

  11. H.-M. Kim, H. Takadama, F. Miyaji, T. Kokubo, S. Nishiguchi, and T. Nakamura, J. Mater. Sci.: Mater. Med. 11, 555 (2000).

    Article  CAS  Google Scholar 

  12. W. Q. Yan, T. Nakamura, M. Kobayashi, H.-M. Kim, F. Miyaji, and T. Kokubo, J. Biomed. Mater. Res. 37, 267 (1997).

    Article  CAS  Google Scholar 

  13. S. Nishiguchi, H. Kato, H. Fujita, M. Oka, H.-M. Kim, T. Kokubo, and T. Nakamura, Biomaterials 22, 2525 (2001).

    Article  CAS  Google Scholar 

  14. T. Kokubo, H.-M. Kim, M. Kawashita, and T. Nakamura, J. Mater. Sci.: Mater. Med. 15, 99 (2004).

    Article  CAS  Google Scholar 

  15. M. Uchida, H.-M. Kim, T. Kokubo, and T. Nakamura, Bioceramics Vol. 12 (eds. H. Ohgushi, G. W. Hastings, and T. Yoshikawa), p. 149, World Scientific, Singapore (1999).

    Google Scholar 

  16. M. Uchida, H.-M. Kim, T. Kokubo, S. Fujibayashi, and T. Nakamura, J. Biomed. Mater. Res. 64A, 164 (2003).

    Article  CAS  Google Scholar 

  17. T. Y. Xiong, X. Y. Cui, H.-M. Kim, M. Kawashita, T. Kokubo, J. Wu, H. Z. Jin, and T. Nakamura, Key Eng. Mater. 254–256, 375 (2004).

    Article  Google Scholar 

  18. M. Kawashita, X. Y. Cui, H.-M. Kim, T. Kokubo, and T. Nakamura, Key Eng. Mater. 254–256, 459 (2004).

    Article  Google Scholar 

  19. X. Cui, H.-M. Kim, M. Kawashita, L. Wang, T. Xiong, T. Kokubo, and T. Nakamura, J. Ceram. Soc. Jpn. 116, 329 (2008).

    Article  CAS  Google Scholar 

  20. X. Cui, H.-M. Kim, M. Kawashita, L. Wang, T. Xiong, T. Kokubo, and T. Nakamura, J. Mater. Sci.: Mater. Med. 19, 1767 (2008).

    Article  CAS  Google Scholar 

  21. X. Cui, H.-M. Kim, M. Kawashita, L. Wang, T. Xiong, T. Kokubo, and T. Nakamura, Dent. Mater. 25, 80 (2009).

    Article  CAS  Google Scholar 

  22. T. Kokubo, H. Kushitani, S. Sakka, T. Kitsugi, and T. Yamamuro, J. Biomed. Mater. Res. 24, 721 (1990).

    Article  CAS  Google Scholar 

  23. B. C. Yang, M. Uchida, H.-M. Kim, X. D. Zhang, and T. Kokubo, Biomaterials 25, 1003 (2004).

    Article  CAS  Google Scholar 

  24. H. Takadama, H.-M. Kim, T. Kokubo, and T. Nakamura, J. Biomed. Mater. Res. 55, 185 (2001).

    Article  CAS  Google Scholar 

  25. H. Takadama, H.-M. Kim, T. Kokubo, and T. Nakamura, J. Biomed. Mater. Res. 57, 441 (2001).

    Article  CAS  Google Scholar 

  26. T. Kokubo, H.-M. Kim, and M. Kawashita, Biomaterials 24, 2161 (2003).

    Article  CAS  Google Scholar 

  27. Joint Committee on Powder Diffraction Standards-International Center for Diffraction Data, Joint Committee on Powder Diffraction Standards Card. 2111276, Rutile.

  28. Joint Committee on Powder Diffraction Standards-International Center for Diffraction Data, Joint Committee on Powder Diffraction Standards Card. 721243, Hydroxyapatite.

  29. R. Z. LeGeros and J. P. LeGeros, An Introduction to Bioceramics (eds. L. L. Hench and J. Wilson), p. 139, World Scientific, Singapore (1993).

    Google Scholar 

  30. M. C. Bryan, Nature 260, 727 (1976).

    Article  Google Scholar 

  31. J. M. Wu, S. Hayakawa, K. Tsuru, and A. Osaka, J. Am. Ceram. Soc. 87, 1635 (2004).

    Article  CAS  Google Scholar 

  32. X. X. Wang, S. Hayakawa, K. Tsuru, and A. Osaka, J. Biomed. Mater. Res. 52, 171 (2000).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masakazu Kawashita.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cui, X., Kim, HM., Kawashita, M. et al. Apatite formation on anodized Ti-6Al-4V alloy in simulated body fluid. Met. Mater. Int. 16, 407–412 (2010). https://doi.org/10.1007/s12540-010-0610-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12540-010-0610-x

Keywords

Navigation